MIRO and IRbase: IT tools for the epidemiological monitoring of insecticide resistance in mosquito disease vectors

dc.contributor.advisor	Dialynas, Emmanuel	en
dc.contributor.advisor	Διαλυνάς, Εμμανουήλ	el
dc.contributor.author	Τοπαλής, Παντελής	el
dc.contributor.author	Topalis, Pantelis	en
dc.contributor.author	Vontas, John	en
dc.contributor.author	Louis, Christos	en
dc.contributor.author	Βοντάς, Ιωάννης	el
dc.contributor.author	Λούης, Χρήστος	el
dc.date.accessioned	2014-06-06T06:49:28Z
dc.date.available	2014-06-06T06:49:28Z
dc.identifier.uri	http://dx.doi.org/10.1371/journal.pntd.0000465	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/4612
dc.title	MIRO and IRbase: IT tools for the epidemiological monitoring of insecticide resistance in mosquito disease vectors	en
heal.type	journalArticle	en
heal.keyword	MIRO	en
heal.keyword	IRbase	en
heal.keyword	Disease vectors	en
heal.keyword	Mosquito control	en
heal.keyword	Factual database	en
heal.keyword	Mosquito Insecticide Resistance Ontology	en
heal.keyword	Insecticide resistance	en
heal.identifier.primary	10.1371/journal.pntd.0000465	en
heal.identifier.secondary	e465	en
heal.recordProvider	Γεωπονικό Πανεπιστήμιο Αθηνών/Επιστήμη Φυτικής Παραγωγής	el
heal.recordProvider	Ινστιτούτο Μοριακής Βιολογίας και Βιοτεχνολογίας/Ίδρυμα Έρευνας και Τεχνολογίας Ηρακλείου Κρήτης	el
heal.recordProvider	Πανεπιστήμιο Κρήτης/Τμήμα Βιολογίας	el
heal.recordProvider	Liverpool School of Tropical Medicine/Vector Research	en
heal.publicationDate	2009-07-23	en
heal.bibliographicCitation	Dialynas, Emmanuel et.al. MIRO and IRbase: IT tools for the epidemiological monitoring of insecticide resistance in mosquito disease vectors, PLoS Neglected Tropical Diseases, vol. 3 (6), pp 1-9, PLOS 2009	en
heal.abstract	Monitoring of insect vector populations with respect to their susceptibility to one or more insecticides is a crucial element of the strategies used for the control of arthropod-borne diseases. This management task can nowadays be achieved more efficiently when assisted by IT (Information Technology) tools, ranging from modern integrated databases to GIS (Geographic Information System). Here we describe an application ontology that we developed de novo, and a specially designed database that, based on this ontology, can be used for the purpose of controlling mosquitoes and, thus, the diseases that they transmit. The ontology, named MIRO for Mosquito Insecticide Resistance Ontology, developed using the OBO-Edit software, describes all pertinent aspects of insecticide resistance, including specific methodology and mode of action. MIRO, then, forms the basis for the design and development of a dedicated database, IRbase, constructed using open source software, which can be used to retrieve data on mosquito populations in a temporally and spatially separate way, as well as to map the output using a Google Earth interface. The dependency of the database on the MIRO allows for a rational and efficient hierarchical search possibility. The fact that the MIRO complies with the rules set forward by the OBO (Open Biomedical Ontologies) Foundry introduces cross-referencing with other biomedical ontologies and, thus, both MIRO and IRbase are suitable as parts of future comprehensive surveillance tools and decision support systems that will be used for the control of vector-borne diseases. MIRO is downloadable from and IRbase is accessible at VectorBase, the NIAID-sponsored open access database for arthropod vectors of disease.	en
heal.journalName	PLoS Neglected Tropical Diseases	en
dc.identifier.doi	10.1371/journal.pntd.0000465	en