| dc.contributor.author |
Haroutounian, SA |
en |
| dc.contributor.author |
Couladouros, EA |
en |
| dc.date.accessioned |
2014-06-06T06:43:04Z |
|
| dc.date.available |
2014-06-06T06:43:04Z |
|
| dc.date.issued |
1996 |
en |
| dc.identifier.issn |
0947-3440 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/991 |
|
| dc.subject |
Grignard reaction |
en |
| dc.subject |
beta-hydrogen transfer |
en |
| dc.subject |
C-benzylation |
en |
| dc.subject.classification |
Chemistry, Multidisciplinary |
en |
| dc.subject.other |
IRREVERSIBLE ENZYME-INHIBITORS |
en |
| dc.subject.other |
CHOLINE ACETYLTRANSFERASE |
en |
| dc.subject.other |
BINDING-AFFINITY |
en |
| dc.subject.other |
DERIVATIVES |
en |
| dc.subject.other |
AGENTS |
en |
| dc.title |
Reaction of 4'-benzyloxy-2(4-pyridinyl)acetophenone with ethylmagnesium chloride: Unusual C-benzylation and in situ reduction by beta-hydrogen transfer |
en |
| heal.type |
journalArticle |
en |
| heal.language |
English |
en |
| heal.publicationDate |
1996 |
en |
| heal.abstract |
In solution, 4'-benzyloxy-2-(4-pyridinyl)acetophenone (I) mainly exists as enol 4 which does not undergo typical Grignard addition reactions. Treatment with an excess of ethyl-magnesium chloride, however, initiates an unusual sequence of transformations leading to formation of the C-benzylated compounds 2 and 3. |
en |
| heal.publisher |
VCH PUBLISHERS INC |
en |
| heal.journalName |
LIEBIGS ANNALEN |
en |
| dc.identifier.issue |
7 |
en |
| dc.identifier.isi |
ISI:A1996UW66100012 |
en |
| dc.identifier.spage |
1139 |
en |
| dc.identifier.epage |
1141 |
en |