| dc.contributor.author |
Couladouros, EA |
en |
| dc.contributor.author |
Soufli, IC |
en |
| dc.date.accessioned |
2014-06-06T06:42:42Z |
|
| dc.date.available |
2014-06-06T06:42:42Z |
|
| dc.date.issued |
1994 |
en |
| dc.identifier.issn |
00404039 |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1016/S0040-4039(00)73369-7 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/772 |
|
| dc.subject.other |
antineoplastic agent |
en |
| dc.subject.other |
combretastatin d2 |
en |
| dc.subject.other |
macrocyclic compound |
en |
| dc.subject.other |
unclassified drug |
en |
| dc.subject.other |
article |
en |
| dc.subject.other |
drug synthesis |
en |
| dc.subject.other |
reaction analysis |
en |
| dc.title |
Synthesis of combretastatin D-2. An efficient route to caffrane macrolactones |
en |
| heal.type |
journalArticle |
en |
| heal.identifier.primary |
10.1016/S0040-4039(00)73369-7 |
en |
| heal.publicationDate |
1994 |
en |
| heal.abstract |
Combretastatin D-2, (1), was synthesized via a 10 step sequence. Macrolactonization was performed saturated substrate 12 in high yield and the double bond was established via dehalogenation of intermediate 15. |
en |
| heal.journalName |
Tetrahedron Letters |
en |
| dc.identifier.issue |
25 |
en |
| dc.identifier.volume |
35 |
en |
| dc.identifier.doi |
10.1016/S0040-4039(00)73369-7 |
en |
| dc.identifier.spage |
4409 |
en |
| dc.identifier.epage |
4412 |
en |