Total synthesis of taxol

dc.contributor.author	Nicolaou, K	en
dc.contributor.author	Yang, Z	en
dc.contributor.author	Liu, J	en
dc.contributor.author	Ueno, H	en
dc.contributor.author	Nantermet, P	en
dc.contributor.author	Guy, R	en
dc.contributor.author	Claiborne, C	en
dc.contributor.author	Renaud, J	en
dc.contributor.author	Couladouros, E	en
dc.contributor.author	Paulvannan, K	en
dc.contributor.author	Sorensen, E	en
dc.date.accessioned	2014-06-06T06:42:40Z
dc.date.available	2014-06-06T06:42:40Z
dc.date.issued	1994	en
dc.identifier.uri	http://dx.doi.org/10.1038/367630a0	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/752
dc.subject	Cancer Patient	en
dc.subject	Ecological Impact	en
dc.subject	Natural Product	en
dc.subject	Total Synthesis	en
dc.title	Total synthesis of taxol	en
heal.type	journalArticle	en
heal.identifier.primary	10.1038/367630a0	en
heal.publicationDate	1994	en
heal.abstract	TAXOL1-4, a substance originally isolated from the Pacific yew tree (Taxus brevifolia) more than two decades ago, has recently been approved for the clinical treatment of cancer patients. Hailed as having provided one of the most significant advances in cancer therapy5, this molecule exerts its anticancer activity by inhibiting mitosis through enhancement of the polymerization of tubulin and consequent stabilization	en
heal.journalName	Nature	en
dc.identifier.doi	10.1038/367630a0	en