The role of organic selenium in cadmium toxicity: Effects on broiler performance and health status

dc.contributor.author	Al-Waeli, A	en
dc.contributor.author	Zoidis, E	en
dc.contributor.author	Pappas, AC	en
dc.contributor.author	Demiris, N	en
dc.contributor.author	Zervas, G	en
dc.contributor.author	Fegeros, K	en
dc.date.accessioned	2014-06-06T06:52:53Z
dc.date.available	2014-06-06T06:52:53Z
dc.date.issued	2013	en
dc.identifier.issn	17517311	en
dc.identifier.uri	http://dx.doi.org/10.1017/S1751731112001590	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/6236
dc.subject	antioxidant system	en
dc.subject	broiler	en
dc.subject	cadmium toxicity	en
dc.subject	performance	en
dc.subject	selenium-yeast	en
dc.subject.other	cadmium chloride	en
dc.subject.other	selenium	en
dc.subject.other	age	en
dc.subject.other	analysis of variance	en
dc.subject.other	animal	en
dc.subject.other	animal disease	en
dc.subject.other	animal food	en
dc.subject.other	article	en
dc.subject.other	bird disease	en
dc.subject.other	blood examination	en
dc.subject.other	cadmium poisoning	en
dc.subject.other	chemically induced disorder	en
dc.subject.other	chicken	en
dc.subject.other	controlled clinical trial	en
dc.subject.other	controlled study	en
dc.subject.other	food contamination	en
dc.subject.other	mass spectrometry	en
dc.subject.other	metabolism	en
dc.subject.other	randomized controlled trial	en
dc.subject.other	Age Factors	en
dc.subject.other	Analysis of Variance	en
dc.subject.other	Animal Feed	en
dc.subject.other	Animals	en
dc.subject.other	Cadmium Chloride	en
dc.subject.other	Cadmium Poisoning	en
dc.subject.other	Chickens	en
dc.subject.other	Food Contamination	en
dc.subject.other	Hematologic Tests	en
dc.subject.other	Mass Spectrometry	en
dc.subject.other	Poultry Diseases	en
dc.subject.other	Selenium	en
dc.title	The role of organic selenium in cadmium toxicity: Effects on broiler performance and health status	en
heal.type	journalArticle	en
heal.identifier.primary	10.1017/S1751731112001590	en
heal.publicationDate	2013	en
heal.abstract	This work was part of a project designed to assess whether organic selenium (Se) can protect against the toxic effects of cadmium (Cd). A total of 300 1-day-old, as hatched, broilers were randomly distributed in four dietary treatments with five replicate pens per treatment. In T1 treatment, broilers were fed a diet with 0.3 mg/kg added Se, as Se-yeast, without added Cd; in T2, broilers were fed a diet with 0.3 mg/kg Se and 10 mg/kg Cd; in T3, broilers were fed a diet with 0.3 mg/kg Se and 100 mg/kg of Cd; and in T4 treatment broilers were fed a diet with 3 mg/kg Se and 100 mg/kg Cd. The Cd was added to diets T2, T3 and T4 as CdCl2. On the 4th and 6th week, two broilers per replicate pen were killed in order to obtain whole blood, liver, kidney and breast samples. Body mass, feed conversion ratio and mortality were assessed and haematological analyses were performed. Se and Cd levels in tissues were analysed by inductively coupled plasma mass spectrometry. Broilers supplemented with 0.3 mg/kg Se can tolerate low levels of Cd added to the diets, as there were no significant negative effects on the examined performance parameters, whereas addition of excess Cd led to an impairment of broilers' performance. Mortality of broilers did not differ between the four dietary treatments at any interval point or the whole period. The examined haematological parameters such as haematocrit, total blood protein concentration, and leukocytes types ranged within physiological values, revealing no negative health effects after simultaneous Cd and Se addition. The present study indicated that Se can help against the negative effects of Cd, but cannot counteract all of its negative effects. © 2012 The Animal Consortium.	en
heal.journalName	Animal	en
dc.identifier.issue	3	en
dc.identifier.volume	7	en
dc.identifier.doi	10.1017/S1751731112001590	en
dc.identifier.spage	386	en
dc.identifier.epage	393	en