| dc.contributor.author |
Kogiannou, DAA |
en |
| dc.contributor.author |
Kalogeropoulos, N |
en |
| dc.contributor.author |
Kefalas, P |
en |
| dc.contributor.author |
Polissiou, MG |
en |
| dc.contributor.author |
Kaliora, AC |
en |
| dc.date.accessioned |
2014-06-06T06:52:36Z |
|
| dc.date.available |
2014-06-06T06:52:36Z |
|
| dc.date.issued |
2013 |
en |
| dc.identifier.issn |
02786915 |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1016/j.fct.2013.05.027 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/6080 |
|
| dc.subject |
Antiinflammatory |
en |
| dc.subject |
Antiproliferative |
en |
| dc.subject |
GC-MS |
en |
| dc.subject |
Herbal infusions |
en |
| dc.subject |
LC-DAD-MS |
en |
| dc.subject |
NF-κB |
en |
| dc.subject.other |
antiinflammatory agent |
en |
| dc.subject.other |
antioxidant |
en |
| dc.subject.other |
caffeic acid |
en |
| dc.subject.other |
catechin |
en |
| dc.subject.other |
chlorogenic acid |
en |
| dc.subject.other |
chrysin |
en |
| dc.subject.other |
cinnamic acid |
en |
| dc.subject.other |
coumarin |
en |
| dc.subject.other |
epicatechin |
en |
| dc.subject.other |
ferulic acid |
en |
| dc.subject.other |
gallic acid |
en |
| dc.subject.other |
immunoglobulin enhancer binding protein |
en |
| dc.subject.other |
interleukin 8 |
en |
| dc.subject.other |
Matricaria chamomilla extract |
en |
| dc.subject.other |
Mentha pulegium extract |
en |
| dc.subject.other |
naringenin |
en |
| dc.subject.other |
Origanum microphyllum extract |
en |
| dc.subject.other |
origanum vulgare extract |
en |
| dc.subject.other |
para coumaric acid |
en |
| dc.subject.other |
phenol |
en |
| dc.subject.other |
phloretic acid |
en |
| dc.subject.other |
plant extract |
en |
| dc.subject.other |
plant medicinal product |
en |
| dc.subject.other |
protocatechuic acid |
en |
| dc.subject.other |
Satureja thymbra extract |
en |
| dc.subject.other |
Sideritis syriaca extract |
en |
| dc.subject.other |
sinapic acid |
en |
| dc.subject.other |
syringic acid |
en |
| dc.subject.other |
unclassified drug |
en |
| dc.subject.other |
unindexed drug |
en |
| dc.subject.other |
vannilic acid |
en |
| dc.subject.other |
antiinflammatory activity |
en |
| dc.subject.other |
antioxidant activity |
en |
| dc.subject.other |
article |
en |
| dc.subject.other |
cancer cell culture |
en |
| dc.subject.other |
cell proliferation |
en |
| dc.subject.other |
cell strain HT29 |
en |
| dc.subject.other |
cell strain PC3 |
en |
| dc.subject.other |
controlled study |
en |
| dc.subject.other |
drug mechanism |
en |
| dc.subject.other |
drug targeting |
en |
| dc.subject.other |
human |
en |
| dc.subject.other |
human cell |
en |
| dc.subject.other |
mass fragmentography |
en |
| dc.subject.other |
oregano |
en |
| dc.subject.other |
Origanum microphyllum |
en |
| dc.subject.other |
satureja thymbra |
en |
| dc.subject.other |
savory |
en |
| dc.subject.other |
Sideritis syriaca |
en |
| dc.subject.other |
tea |
en |
| dc.subject.other |
Origanum |
en |
| dc.title |
Herbal infusions; their phenolic profile, antioxidant and anti-inflammatory effects in HT29 and PC3 cells |
en |
| heal.type |
journalArticle |
en |
| heal.identifier.primary |
10.1016/j.fct.2013.05.027 |
en |
| heal.publicationDate |
2013 |
en |
| heal.abstract |
In this survey, we analyzed the phenolic profile of six herbal infusions namely Cretan marjoram, pink savory, oregano, mountain tea, pennyroyal and chamomile by LCDAD-MS and by GC-MS. Further, we investigated their anticarcinogenic effect as to their ability to (a) scavenge free radicals (b) inhibit proliferation (c) decrease IL-8 levels and (d) regulate nuclear factor-kappa B in epithelial colon cancer (HT29) and prostate (PC3) cancer cells. All herbal infusions exhibited antiradical activity correlated positevely with total phenolic content. Further, infusions exhibited the potential to inhibit cell proliferation and to reduce IL-8 levels in HT29 colon and PC3 prostate cancer cells. The molecular target for chamomile in HT29 seemed to be the NF-κB, while for the other herbal infusions needs to be identified. This study is the first to show the potential chemopreventive activity of infusions prepared from the examined herbs. © 2013 Elsevier Ltd. |
en |
| heal.journalName |
Food and Chemical Toxicology |
en |
| dc.identifier.volume |
61 |
en |
| dc.identifier.doi |
10.1016/j.fct.2013.05.027 |
en |
| dc.identifier.spage |
152 |
en |
| dc.identifier.epage |
159 |
en |