European surveillance for pantropic canine coronavirus

dc.contributor.author	Decaro, N	en
dc.contributor.author	Cordonnier, N	en
dc.contributor.author	Demeter, Z	en
dc.contributor.author	Egberink, H	en
dc.contributor.author	Elia, G	en
dc.contributor.author	Grellet, A	en
dc.contributor.author	Poder, SL	en
dc.contributor.author	Mari, V	en
dc.contributor.author	Martella, V	en
dc.contributor.author	Ntafis, V	en
dc.contributor.author	Von Reitzenstein, M	en
dc.contributor.author	Rottier, PJ	en
dc.contributor.author	Rusvai, M	en
dc.contributor.author	Shields, S	en
dc.contributor.author	Xylouri, E	en
dc.contributor.author	Xu, Z	en
dc.contributor.author	Buonavoglia, C	en
dc.date.accessioned	2014-06-06T06:52:30Z
dc.date.available	2014-06-06T06:52:30Z
dc.date.issued	2013	en
dc.identifier.issn	00951137	en
dc.identifier.uri	http://dx.doi.org/10.1128/JCM.02466-12	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/6048
dc.subject.other	virus RNA	en
dc.subject.other	virus spike protein	en
dc.subject.other	5' untranslated region	en
dc.subject.other	animal cell	en
dc.subject.other	animal tissue	en
dc.subject.other	article	en
dc.subject.other	Coronavirus	en
dc.subject.other	Coronavirus infection	en
dc.subject.other	dog disease	en
dc.subject.other	European Union	en
dc.subject.other	gene cluster	en
dc.subject.other	gene sequence	en
dc.subject.other	geographic distribution	en
dc.subject.other	health survey	en
dc.subject.other	nonhuman	en
dc.subject.other	nucleotide sequence	en
dc.subject.other	phylogeny	en
dc.subject.other	priority journal	en
dc.subject.other	virus detection	en
dc.subject.other	virus strain	en
dc.subject.other	Animal Structures	en
dc.subject.other	Animals	en
dc.subject.other	Cluster Analysis	en
dc.subject.other	Coronavirus Infections	en
dc.subject.other	Coronavirus, Canine	en
dc.subject.other	Dog Diseases	en
dc.subject.other	Dogs	en
dc.subject.other	Europe	en
dc.subject.other	Genetic Variation	en
dc.subject.other	Membrane Glycoproteins	en
dc.subject.other	Molecular Sequence Data	en
dc.subject.other	Phylogeny	en
dc.subject.other	Prevalence	en
dc.subject.other	Sequence Analysis, DNA	en
dc.subject.other	Viral Envelope Proteins	en
dc.subject.other	Animalia	en
dc.subject.other	Canine coronavirus	en
dc.subject.other	Canis familiaris	en
dc.title	European surveillance for pantropic canine coronavirus	en
heal.type	journalArticle	en
heal.identifier.primary	10.1128/JCM.02466-12	en
heal.publicationDate	2013	en
heal.abstract	Highly virulent pantropic canine coronavirus (CCoV) strains belonging to subtype IIa were recently identified in dogs. To assess the distribution of such strains in Europe, tissue samples were collected from 354 dogs that had died after displaying systemic disease in France (n = 92), Hungary (n = 75), Italy (n = 69), Greece (n = 87), The Netherlands (n = 27), Belgium (n = 4), and Bulgaria (n = 1). A total of 124 animals tested positive for CCoV, with 33 of them displaying the virus in extraintestinal tissues. Twenty-four CCoV strains (19.35% of the CCoV-positive dogs) detected in internal organs were characterized as subtype IIa and consequently assumed to be pantropic CCoVs. Sequence and phylogenetic analyses of the 5′ end of the spike protein gene showed that pantropic CCoV strains are closely related to each other, with the exception of two divergent French viruses that clustered with enteric strains. Copyright © 2013, American Society for Microbiology. All Rights Reserved.	en
heal.journalName	Journal of Clinical Microbiology	en
dc.identifier.issue	1	en
dc.identifier.volume	51	en
dc.identifier.doi	10.1128/JCM.02466-12	en
dc.identifier.spage	83	en
dc.identifier.epage	88	en