Validation of Two Variations of the QuEChERS Method for the Determination of Multiclass Pesticide Residues in Cereal-Based Infant Foods by LC-MS/MS

dc.contributor.author	Anagnostopoulos, CJ	en
dc.contributor.author	Aplada Sarli, P	en
dc.contributor.author	Liapis, K	en
dc.contributor.author	Haroutounian, SA	en
dc.contributor.author	Miliadis, GE	en
dc.date.accessioned	2014-06-06T06:52:12Z
dc.date.available	2014-06-06T06:52:12Z
dc.date.issued	2012	en
dc.identifier.issn	19369751	en
dc.identifier.uri	http://dx.doi.org/10.1007/s12161-011-9296-z	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/5896
dc.subject	Cereal-based infant foods	en
dc.subject	LC-MS-MS	en
dc.subject	Pesticide residues	en
dc.subject	QuEChERS	en
dc.subject	Validation	en
dc.subject.other	Infant food	en
dc.subject.other	LC-MS-MS	en
dc.subject.other	Pesticide residue	en
dc.subject.other	QuEChERS	en
dc.subject.other	Validation	en
dc.subject.other	Biomolecules	en
dc.subject.other	Laws and legislation	en
dc.subject.other	Liquid chromatography	en
dc.subject.other	Mass spectrometry	en
dc.subject.other	Metabolites	en
dc.subject.other	Pesticides	en
dc.subject.other	Chemical contamination	en
dc.title	Validation of Two Variations of the QuEChERS Method for the Determination of Multiclass Pesticide Residues in Cereal-Based Infant Foods by LC-MS/MS	en
heal.type	journalArticle	en
heal.identifier.primary	10.1007/s12161-011-9296-z	en
heal.publicationDate	2012	en
heal.abstract	Over the past years to ensure food safety and particular for food that intend to be consumed by infants and young children, the European Union has adopted specific legislation concerning the control of pesticide residue levels in that kind of food. In this paper, a liquid chromatography tandem quadrupole mass spectrometry (LC-MS/MS) multiresidue method for the simultaneous analysis of 23 pesticides and metabolites chosen according to the Commission Directives 2006/141/EC, 2006/125/EC, and 96 multiclass pesticides and metabolites chosen according to their physicochemical properties is presented and validated. The extraction procedure is based on three modifications of the quick, easy, cheap, effective, rugged, and safe method according to the analyte. The analytical performance was demonstrated by the analysis of extracts from cereal-based infant foods, spiked at two concentration levels for each pesticide or metabolite. Good sensitivity and selectivity of the method were obtained with limits of quantification at 10 or 3 μg/kg, depending on the analyte. All pesticides and metabolites, except six cases, gave recoveries in the range of 60. 4-125. 4%, with relative standard deviations less than 29. 7%, for both validation levels. © 2011 Springer Science+Business Media, LLC.	en
heal.journalName	Food Analytical Methods	en
dc.identifier.issue	4	en
dc.identifier.volume	5	en
dc.identifier.doi	10.1007/s12161-011-9296-z	en
dc.identifier.spage	664	en
dc.identifier.epage	683	en