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Ultra-thin layer chromatography and surface enhanced Raman spectroscopy on silver nanorod array substrates prepared by oblique angle deposition

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dc.contributor.author Chen, J en
dc.contributor.author Abell, J en
dc.contributor.author Huang, Y-W en
dc.contributor.author Zhao, Y en
dc.date.accessioned 2014-06-06T06:52:11Z
dc.date.available 2014-06-06T06:52:11Z
dc.date.issued 2012 en
dc.identifier.issn 0277786X en
dc.identifier.uri http://dx.doi.org/10.1117/12.918763 en
dc.identifier.uri http://62.217.125.90/xmlui/handle/123456789/5891
dc.subject on-chip separation en
dc.subject SERS en
dc.subject silver nanorod array en
dc.subject ultra-thin layer chromatography en
dc.subject.other Brilliant Blue en
dc.subject.other Brilliant blue FCF en
dc.subject.other Detection of chemicals en
dc.subject.other Food colorants en
dc.subject.other Mobile phase en
dc.subject.other Oblique-angle deposition en
dc.subject.other On-chip separations en
dc.subject.other SERS en
dc.subject.other SERS spectrum en
dc.subject.other Silver nanorod arrays en
dc.subject.other Silver nanorods en
dc.subject.other Small molecules en
dc.subject.other Surface enhanced Raman spectroscopy en
dc.subject.other Ultrathin layers en
dc.subject.other Chromatographic analysis en
dc.subject.other Environmental technology en
dc.subject.other Lactic acid en
dc.subject.other Light transmission en
dc.subject.other Mixtures en
dc.subject.other Nanorods en
dc.subject.other Raman spectroscopy en
dc.subject.other Separation en
dc.subject.other Silver en
dc.subject.other Thin layer chromatography en
dc.subject.other Substrates en
dc.title Ultra-thin layer chromatography and surface enhanced Raman spectroscopy on silver nanorod array substrates prepared by oblique angle deposition en
heal.type conferenceItem en
heal.identifier.primary 10.1117/12.918763 en
heal.identifier.secondary 836605 en
heal.publicationDate 2012 en
heal.abstract We demonstrate the potential use of silver nanorod (AgNR) array substrates for on-chip separation and detection of chemical mixtures by ultra-thin layer chromatography (UTLC) and surface enhanced Raman spectroscopy (SERS). The capability of the AgNR substrates to separate different compounds in a mixture was explored using a mixture of the food colorant Brilliant Blue FCF and lactic acid, and the mixtures of Methylene Violet and BSA at various concentrations. After the UTLC process, spatially-resolved SERS spectra were collected along the mobile phase development direction and the intensities of specific SERS peaks from each component were used to generate chromatograms. The AgNR substrates demonstrate the capability of separating Brilliant Blue from lactic acid, as well as revealing the SERS signal of Methylene Violet from the massive BSA background after a simple UTLC step. This technique may have significant practical implications in actual detection of small molecules from complex food or clinical backgrounds. © 2012 SPIE. en
heal.journalName Proceedings of SPIE - The International Society for Optical Engineering en
dc.identifier.volume 8366 en
dc.identifier.doi 10.1117/12.918763 en


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