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Adherence to the Mediterranean diet and albuminuria levels in Greek adolescents: Data from the Leontio Lyceum ALbuminuria (3L study)

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dc.contributor.author Mazaraki, A en
dc.contributor.author Tsioufis, C en
dc.contributor.author Dimitriadis, K en
dc.contributor.author Tsiachris, D en
dc.contributor.author Stefanadi, E en
dc.contributor.author Zampelas, A en
dc.contributor.author Richter, D en
dc.contributor.author Mariolis, A en
dc.contributor.author Panagiotakos, D en
dc.contributor.author Tousoulis, D en
dc.contributor.author Stefanadis, C en
dc.date.accessioned 2014-06-06T06:51:11Z
dc.date.available 2014-06-06T06:51:11Z
dc.date.issued 2011 en
dc.identifier.issn 09543007 en
dc.identifier.uri http://dx.doi.org/10.1038/ejcn.2010.244 en
dc.identifier.uri http://62.217.125.90/xmlui/handle/123456789/5371
dc.subject 3L study (Leontio Lyceum ALbuminuria Study) en
dc.subject Albuminuria en
dc.subject atherosclerosis en
dc.subject.other albumin en
dc.subject.other adolescent en
dc.subject.other age distribution en
dc.subject.other albumin blood level en
dc.subject.other albuminuria en
dc.subject.other article en
dc.subject.other body mass en
dc.subject.other child en
dc.subject.other child nutrition en
dc.subject.other cohort analysis en
dc.subject.other controlled study en
dc.subject.other feedback system en
dc.subject.other female en
dc.subject.other Greece en
dc.subject.other health program en
dc.subject.other human en
dc.subject.other Leontio Lyceum Albuminuria en
dc.subject.other lifestyle en
dc.subject.other male en
dc.subject.other Mediterranean diet en
dc.subject.other microalbuminuria en
dc.subject.other negative feedback en
dc.subject.other normal human en
dc.subject.other patient compliance en
dc.subject.other practice guideline en
dc.subject.other pulse pressure en
dc.subject.other school child en
dc.subject.other sex ratio en
dc.subject.other systolic blood pressure en
dc.subject.other waist circumference en
dc.subject.other Adolescent en
dc.subject.other Age Factors en
dc.subject.other Albuminuria en
dc.subject.other Blood Pressure en
dc.subject.other Body Mass Index en
dc.subject.other Child en
dc.subject.other Cohort Studies en
dc.subject.other Creatinine en
dc.subject.other Diet, Mediterranean en
dc.subject.other Female en
dc.subject.other Greece en
dc.subject.other Guideline Adherence en
dc.subject.other Humans en
dc.subject.other Male en
dc.subject.other Sex Factors en
dc.title Adherence to the Mediterranean diet and albuminuria levels in Greek adolescents: Data from the Leontio Lyceum ALbuminuria (3L study) en
heal.type journalArticle en
heal.identifier.primary 10.1038/ejcn.2010.244 en
heal.publicationDate 2011 en
heal.abstract Background/Objectives: Mediterranean diet has favorable effects on the cardiovascular system, whereas albuminuria is associated with atherosclerosis progression. The aim of the study was to assess the relationships of adherence rates to the Mediterranean diet with albumin to creatinine ratio (ACR), in a cohort of Greek adolescents who participated in the Leontio Lyceum ALbuminuria (3L) study.Subjects/Methods: In a total of 365 adolescents 12-17 years of age included in 3L study, ACR values were determined in a morning-spot urine.Results: The Mediterranean diet Quality Index for children and adolescents (KIDMED) was estimated and accordingly subjects were divided into those with high (≥8), average (4-7) and low (≤3) score. Adolescents with low (n = 153, 42%) compared with those with average (n = 187, 51.2%) and high (n = 25, 6.8%) KIDMED score were characterized by greater ACR values (22.4 vs 13.4 vs 12.1 mg/g, P<0.05) even after adjustment for confounders. In the total population, KIDMED score was related to body mass index (r=0.122, P=0.02), waist circumference (r=0.118, P=0.02), systolic blood pressure (BP) (r=0.119, P=0.023), whereas it was negatively associated with ACR (r=-0.111, P=0.041). Regarding ACR, it was associated with age (r=-0.11, P=0.044), male sex (r=0.16, P=0.003), body mass index (r=-0.131, P=0.016) and systolic BP (r=-0.144, P=0.008).Conclusions: Adolescents who adhere to the Mediterranean diet exhibit lower levels of albuminuria, independently of demographic and hemodynamic confounders. The inverse relation of KIDMED index with ACR suggests a close link of accelerated vascular damage reflected by albuminuria with low adherence to this favorable diet of the Mediterranean basin. © 2011 Macmillan Publishers Limited All rights reserved. en
heal.journalName European Journal of Clinical Nutrition en
dc.identifier.issue 2 en
dc.identifier.volume 65 en
dc.identifier.doi 10.1038/ejcn.2010.244 en
dc.identifier.spage 219 en
dc.identifier.epage 225 en


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