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A predictive model of short cervix at 20-24 weeks using first-trimester cervical length measurement and maternal history

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dc.contributor.author Souka, AP en
dc.contributor.author Papastefanou, I en
dc.contributor.author Michalitsi, V en
dc.contributor.author Papadopoulos, GK en
dc.contributor.author Kassanos, D en
dc.date.accessioned 2014-06-06T06:51:10Z
dc.date.available 2014-06-06T06:51:10Z
dc.date.issued 2011 en
dc.identifier.issn 01973851 en
dc.identifier.uri http://dx.doi.org/10.1002/pd.2683 en
dc.identifier.uri http://62.217.125.90/xmlui/handle/123456789/5365
dc.subject Cervical incompetence en
dc.subject First-trimester cervical length en
dc.subject Preterm delivery en
dc.subject Short cervix en
dc.subject Transvaginal ultrasound en
dc.subject.other adolescent en
dc.subject.other adult en
dc.subject.other article en
dc.subject.other clinical article en
dc.subject.other controlled study en
dc.subject.other female en
dc.subject.other first trimester pregnancy en
dc.subject.other gynecological examination en
dc.subject.other human en
dc.subject.other longitudinal study en
dc.subject.other measurement en
dc.subject.other nuchal translucency measurement en
dc.subject.other pregnant woman en
dc.subject.other premature labor en
dc.subject.other priority journal en
dc.subject.other short uterine cervix en
dc.subject.other transvaginal echography en
dc.subject.other uterine cervix en
dc.subject.other uterine cervix disease en
dc.subject.other Adolescent en
dc.subject.other Adult en
dc.subject.other Cervical Length Measurement en
dc.subject.other Cervix Uteri en
dc.subject.other Feasibility Studies en
dc.subject.other Female en
dc.subject.other Humans en
dc.subject.other Middle Aged en
dc.subject.other Models, Biological en
dc.subject.other Pregnancy en
dc.subject.other Pregnancy Complications en
dc.subject.other Pregnancy Trimester, First en
dc.subject.other Prospective Studies en
dc.subject.other Uterine Cervical Diseases en
dc.subject.other Young Adult en
dc.title A predictive model of short cervix at 20-24 weeks using first-trimester cervical length measurement and maternal history en
heal.type journalArticle en
heal.identifier.primary 10.1002/pd.2683 en
heal.publicationDate 2011 en
heal.abstract Objectives: To develop a model for the prediction of short cervix ( ≤ 15 mm) at 20-24 weeks by combining maternal history and transvaginal ultrasonographic measurement of cervical length at 11-14 weeks. To explore the value of an additional ultrasound examination of the cervix at about 17 weeks. Methods: Longitudinal prospective study in 800 unselected pregnant women presenting for first-trimester ultrasound assessment by nuchal translucency and serum biochemistry. Cervical length was evaluated transvaginally between 11 weeks and 13 weeks and 6 days (cx1), at 16-19 weeks (cx2) and 20-24 weeks (cx3). Backward multiple logistic regression analysis with cx3 ≤ 15 mm as the dependent variable was used to identify the predictors of a short cervix at 20-24 weeks. Results: Cx1 and history of preterm delivery were significant independent contributors of a short cervix at 20-24 weeks [area under the curve (AUC 0.808, p < 0.001, Model) 1]. Furthermore, the cx1/cx2 ratio was a significant independent predictor of a short cervix at 20-24 weeks (odds ratio = 58.325 p = 0.012). The addition of the cx1/cx2 ratio improved the model (AUC = 0.878, p < 0.001, Model 2). +Conclusions: A short cervix at 20-24 weeks can be predicted at the 11-14 weeks scan. The addition of a cervical measurement at about 17 weeks can improve the prediction model. Copyright © 2011 John Wiley & Sons, Ltd. en
heal.journalName Prenatal Diagnosis en
dc.identifier.issue 2 en
dc.identifier.volume 31 en
dc.identifier.doi 10.1002/pd.2683 en
dc.identifier.spage 202 en
dc.identifier.epage 206 en


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