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Trichinella spiralis: Differential effect of host bile on the in vitro invasion of infective larvae into epithelial cells

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dc.contributor.author Theodoropoulos, G en
dc.contributor.author Petrakos, G en
dc.date.accessioned 2014-06-06T06:50:46Z
dc.date.available 2014-06-06T06:50:46Z
dc.date.issued 2010 en
dc.identifier.issn 00144894 en
dc.identifier.uri http://dx.doi.org/10.1016/j.exppara.2010.05.013 en
dc.identifier.uri http://62.217.125.90/xmlui/handle/123456789/5151
dc.subject Bile en
dc.subject Epithelial cells en
dc.subject Fox en
dc.subject Invasion en
dc.subject Pig en
dc.subject T. nativa en
dc.subject T. nelsoni en
dc.subject T. spiralis en
dc.subject Trichinella en
dc.subject.other animal cell en
dc.subject.other article en
dc.subject.other bile en
dc.subject.other cell damage en
dc.subject.other cell specificity en
dc.subject.other cell strain en
dc.subject.other controlled study en
dc.subject.other epithelium cell en
dc.subject.other fox en
dc.subject.other host parasite interaction en
dc.subject.other host susceptibility en
dc.subject.other in vitro study en
dc.subject.other larva en
dc.subject.other molecular weight en
dc.subject.other monolayer culture en
dc.subject.other nonhuman en
dc.subject.other parasite virulence en
dc.subject.other priority journal en
dc.subject.other swine en
dc.subject.other Trichinella spiralis en
dc.subject.other trichinosis en
dc.subject.other Animals en
dc.subject.other Bile en
dc.subject.other Cell Line en
dc.subject.other Disease Susceptibility en
dc.subject.other Dogs en
dc.subject.other Epithelial Cells en
dc.subject.other Foxes en
dc.subject.other Host-Parasite Interactions en
dc.subject.other Larva en
dc.subject.other Rats en
dc.subject.other Swine en
dc.subject.other Trichinella spiralis en
dc.subject.other Trichinellosis en
dc.subject.other Suidae en
dc.subject.other Trichinella en
dc.subject.other Trichinella nativa en
dc.subject.other Trichinella nelsoni en
dc.subject.other Trichinella spiralis en
dc.title Trichinella spiralis: Differential effect of host bile on the in vitro invasion of infective larvae into epithelial cells en
heal.type journalArticle en
heal.identifier.primary 10.1016/j.exppara.2010.05.013 en
heal.publicationDate 2010 en
heal.abstract The differential effect of fox and pig bile and its corresponding low molecular weight fraction (LMW) was investigated on the in vitro invasion of MDCK-AA7 epithelial cell monolayers by Trichinella spiralis muscle larvae. Seven invasion experiments were performed and a total of 274 cell monolayers were examined. Fox and pig raw bile at 1:10 and 1:20 dilution and their LMW fractions at 1:10 dilution activated T. spiralis larvae to invade the cell monolayers. In addition, fox raw bile caused significantly larger cell damage than pig raw bile at both dilutions. The area of cell damage was larger at 1:10 than at 1:20 dilution for both fox and pig raw bile (p<0.05). On the other hand, there was no significant difference between the areas of cell damage caused by the LMW fractions of fox and pig bile. It is concluded that differences between host bile actions may account for differences in host susceptibility to T. spiralis. © Elsevier Inc. en
heal.journalName Experimental Parasitology en
dc.identifier.issue 4 en
dc.identifier.volume 126 en
dc.identifier.doi 10.1016/j.exppara.2010.05.013 en
dc.identifier.spage 441 en
dc.identifier.epage 444 en


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