| dc.contributor.author |
KOKOTOS, G |
en |
| dc.contributor.author |
CONSTANTINOUKOKOTOU, V |
en |
| dc.contributor.author |
FERNANDEZ, ED |
en |
| dc.contributor.author |
TOTH, I |
en |
| dc.contributor.author |
GIBBONS, WA |
en |
| dc.date.accessioned |
2014-06-06T06:42:11Z |
|
| dc.date.available |
2014-06-06T06:42:11Z |
|
| dc.date.issued |
1992 |
en |
| dc.identifier.issn |
0170-2041 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/473 |
|
| dc.subject |
AMINO ACIDS |
en |
| dc.subject |
SPHINGOSINES |
en |
| dc.subject |
CERAMIDES |
en |
| dc.subject |
AMINO ALCOHOLS |
en |
| dc.subject |
1,2-DIAMINES |
en |
| dc.subject.classification |
Chemistry, Multidisciplinary |
en |
| dc.title |
LIPIDIC PEPTIDES .14. CONVERSION OF RACEMIC LIPIDIC AMINO-ACIDS INTO SPHINGOSINE AND CERAMIDE ANALOGS AND 1,2-DIAMINES |
en |
| heal.type |
journalArticle |
en |
| heal.language |
English |
en |
| heal.publicationDate |
1992 |
en |
| heal.abstract |
N-Protected racemic lipidic amino acids 1a-h were converted directly into ceramide analogues 2a-h by chemoselective reduction of their corresponding mixed anhydrides with sodium tetrahydroborate. Conversion of the compounds 1 a, b into the corresponding acyl azides, followed by catalytic hydrogenation gave the N-monoprotected lipidic 1,2-diamines 5a, b. The sphingosine analogues 7a-c and the free 1,2-diamines 6a, b were synthesized by deprotection of the compounds 2a-c and 5 a, b, respectively. |
en |
| heal.publisher |
VCH PUBLISHERS INC |
en |
| heal.journalName |
LIEBIGS ANNALEN DER CHEMIE |
en |
| dc.identifier.issue |
9 |
en |
| dc.identifier.isi |
ISI:A1992JV93500012 |
en |
| dc.identifier.spage |
961 |
en |
| dc.identifier.epage |
964 |
en |