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Electrical impedance spectroscopy of gel embedded neuronal cells based on a novel impedimetric biosensor

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dc.contributor.author Jacobs, T en
dc.contributor.author Valero, T en
dc.contributor.author Naumann, M en
dc.contributor.author Kintzios, S en
dc.contributor.author Hauptmann, P en
dc.date.accessioned 2014-06-06T06:49:39Z
dc.date.available 2014-06-06T06:49:39Z
dc.date.issued 2009 en
dc.identifier.issn 18766196 en
dc.identifier.uri http://dx.doi.org/10.1016/j.proche.2009.07.065 en
dc.identifier.uri http://62.217.125.90/xmlui/handle/123456789/4707
dc.subject Electrical impedance spectroscopy en
dc.subject Gel embedded neuronal cells en
dc.subject Impedimetric biosensor en
dc.subject On-line monitoring en
dc.subject.other Cell viability en
dc.subject.other Conductive properties en
dc.subject.other Electrical impedance spectroscopy en
dc.subject.other Flowthrough en
dc.subject.other Gel concentration en
dc.subject.other Impedance measurement en
dc.subject.other Impedance spectrum en
dc.subject.other Impedimetric biosensor en
dc.subject.other In-between en
dc.subject.other N2a cells en
dc.subject.other Neuroblastoma cells en
dc.subject.other Neuronal cell en
dc.subject.other On-line analysis en
dc.subject.other Online monitoring en
dc.subject.other Thin gel film en
dc.subject.other Electric impedance en
dc.subject.other Electric impedance measurement en
dc.subject.other Gels en
dc.subject.other Monitoring en
dc.subject.other Signal transduction en
dc.subject.other Voltage measurement en
dc.subject.other Biosensors en
dc.title Electrical impedance spectroscopy of gel embedded neuronal cells based on a novel impedimetric biosensor en
heal.type conferenceItem en
heal.identifier.primary 10.1016/j.proche.2009.07.065 en
heal.publicationDate 2009 en
heal.abstract In this contribution we focus on the on-line analysis of neuronal cells embedded in gel matrices by means of variations in their dielectric and conductive properties. For impedance measurement of thin gel films in flow-through regime a novel impedimetric biosensor was developed. A technique for the preparation of gels containing Neuro-2a neuroblastoma cells (N2a) in between the measurement electrodes was set up. Impedance spectra of gels with N2a cells were analyzed and cell viability was tested. Experimental results showed that even at frequencies (>>1 MHz) and a gel concentration of 2 % with ~8300 cells/μL conductive properties dominate the spectrum. © 2009. en
heal.journalName Procedia Chemistry en
dc.identifier.issue 1 en
dc.identifier.volume 1 en
dc.identifier.doi 10.1016/j.proche.2009.07.065 en
dc.identifier.spage 261 en
dc.identifier.epage 264 en


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