| dc.contributor.author |
Valero, T |
en |
| dc.contributor.author |
Jacobs, T |
en |
| dc.contributor.author |
Moschopoulou, G |
en |
| dc.contributor.author |
Naumann, M |
en |
| dc.contributor.author |
Hauptmann, P |
en |
| dc.contributor.author |
Kintzios, S |
en |
| dc.date.accessioned |
2014-06-06T06:49:39Z |
|
| dc.date.available |
2014-06-06T06:49:39Z |
|
| dc.date.issued |
2009 |
en |
| dc.identifier.issn |
18766196 |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1016/j.proche.2009.07.183 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/4706 |
|
| dc.subject |
Electrical impedance spectroscopy |
en |
| dc.subject |
Gel embedded neuronal cells |
en |
| dc.subject |
Impedimetric biosensor |
en |
| dc.subject |
On-line monitoring |
en |
| dc.subject.other |
Acetylcholine receptor |
en |
| dc.subject.other |
Cell stimulation |
en |
| dc.subject.other |
Electrical impedance |
en |
| dc.subject.other |
Electrical impedance spectroscopy |
en |
| dc.subject.other |
Flowthrough |
en |
| dc.subject.other |
Gel films |
en |
| dc.subject.other |
Gel matrix |
en |
| dc.subject.other |
Impedance spectrum |
en |
| dc.subject.other |
Impedimetric biosensor |
en |
| dc.subject.other |
In-between |
en |
| dc.subject.other |
N2a cells |
en |
| dc.subject.other |
Neuroblastoma cells |
en |
| dc.subject.other |
Neuroblastomas |
en |
| dc.subject.other |
Neuronal cell |
en |
| dc.subject.other |
Online monitoring |
en |
| dc.subject.other |
Time-scales |
en |
| dc.subject.other |
Biosensors |
en |
| dc.subject.other |
Electric impedance |
en |
| dc.subject.other |
Electric impedance measurement |
en |
| dc.subject.other |
Signal transduction |
en |
| dc.subject.other |
Voltage measurement |
en |
| dc.subject.other |
Gels |
en |
| dc.title |
Electrical impedance analysis of N2a neuroblastoma cells in gel matrices after ACh-receptor triggering with an impedimetric biosensor |
en |
| heal.type |
conferenceItem |
en |
| heal.identifier.primary |
10.1016/j.proche.2009.07.183 |
en |
| heal.publicationDate |
2009 |
en |
| heal.abstract |
In this contribution triggering of the acetylcholine receptor (AChR) in Neuro2a murine neuroblastoma (N2a) cells was studied by means of electrical impedance analysis. N2a cells were immobilized in a bactoagar gel matrix and stimulated with acetylcholine (ACh). Gel films were prepared in between the electrodes of a novel impedimetric sensor. Devices were integrated in a micro fluidic bioreactor for cell stimulation in flow-through regime. Shifts in the impedance spectra (10 to 110 MHz) of gels showed that AChR triggering is accompanied by an increase in the overall conductivity of the gel in a time scale of tens of minutes. © 2009. |
en |
| heal.journalName |
Procedia Chemistry |
en |
| dc.identifier.issue |
1 |
en |
| dc.identifier.volume |
1 |
en |
| dc.identifier.doi |
10.1016/j.proche.2009.07.183 |
en |
| dc.identifier.spage |
734 |
en |
| dc.identifier.epage |
737 |
en |