A short biomimetic approach to the fully functionalized bicyclic framework of type A acylphloroglucinols

dc.contributor.author	Couladouros, EA	en
dc.contributor.author	Dakanali, M	en
dc.contributor.author	Demadis, KD	en
dc.contributor.author	Vidali, VP	en
dc.date.accessioned	2014-06-06T06:49:38Z
dc.date.available	2014-06-06T06:49:38Z
dc.date.issued	2009	en
dc.identifier.issn	15237060	en
dc.identifier.uri	http://dx.doi.org/10.1021/ol901781n	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/4693
dc.subject.other	bicyclo compound	en
dc.subject.other	drug derivative	en
dc.subject.other	phloroglucinol	en
dc.subject.other	article	en
dc.subject.other	biomimetics	en
dc.subject.other	chemical structure	en
dc.subject.other	chemistry	en
dc.subject.other	cyclization	en
dc.subject.other	stereoisomerism	en
dc.subject.other	synthesis	en
dc.subject.other	X ray crystallography	en
dc.subject.other	Bicyclo Compounds	en
dc.subject.other	Biomimetics	en
dc.subject.other	Crystallography, X-Ray	en
dc.subject.other	Cyclization	en
dc.subject.other	Models, Molecular	en
dc.subject.other	Molecular Structure	en
dc.subject.other	Phloroglucinol	en
dc.subject.other	Stereoisomerism	en
dc.title	A short biomimetic approach to the fully functionalized bicyclic framework of type A acylphloroglucinols	en
heal.type	journalArticle	en
heal.identifier.primary	10.1021/ol901781n	en
heal.publicationDate	2009	en
heal.abstract	A biomimetic approach toward type A polyprenylated acylphlorogluclnols (PPAPs) Is described. The method Is based on a C-alkylation-cation cyclization reaction sequence, leading to a convenient buildup of molecular complexity, employing the simple and readily available deoxycohumulone and an appropriately functionalized hydroxy halide. Thus, a versatile construction of the fully functlonallzed bicyclic framework of type A PPAPs (5) was achieved. © 2009 American Chemical Society.	en
heal.journalName	Organic Letters	en
dc.identifier.issue	19	en
dc.identifier.volume	11	en
dc.identifier.doi	10.1021/ol901781n	en
dc.identifier.spage	4430	en
dc.identifier.epage	4433	en