| dc.contributor.author |
Aliferis, KA |
en |
| dc.contributor.author |
Materzok, S |
en |
| dc.contributor.author |
Paziotou, GN |
en |
| dc.contributor.author |
Chrysayi-Tokousbalides, M |
en |
| dc.date.accessioned |
2014-06-06T06:49:27Z |
|
| dc.date.available |
2014-06-06T06:49:27Z |
|
| dc.date.issued |
2009 |
en |
| dc.identifier.issn |
00456535 |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1016/j.chemosphere.2009.04.025 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/4606 |
|
| dc.subject |
Duckweed |
en |
| dc.subject |
Metabonomics |
en |
| dc.subject |
Phytotoxin |
en |
| dc.subject |
Risk assessment |
en |
| dc.subject.other |
Crude extract |
en |
| dc.subject.other |
Duckweed |
en |
| dc.subject.other |
Ecotoxicological study |
en |
| dc.subject.other |
Glyphosate |
en |
| dc.subject.other |
H NMR spectra |
en |
| dc.subject.other |
Hierarchical cluster analysis |
en |
| dc.subject.other |
Lemna minor |
en |
| dc.subject.other |
Mesotrione |
en |
| dc.subject.other |
Metabolic changes |
en |
| dc.subject.other |
Metabolome |
en |
| dc.subject.other |
Metabonomics |
en |
| dc.subject.other |
Model organisms |
en |
| dc.subject.other |
Multi variate analysis |
en |
| dc.subject.other |
NMR fingerprinting |
en |
| dc.subject.other |
Partial least squares-discriminant analysis |
en |
| dc.subject.other |
Phytotoxic substances |
en |
| dc.subject.other |
Phytotoxin |
en |
| dc.subject.other |
Potential methods |
en |
| dc.subject.other |
Toxicological effects |
en |
| dc.subject.other |
Validated methods |
en |
| dc.subject.other |
Biochemistry |
en |
| dc.subject.other |
Cluster analysis |
en |
| dc.subject.other |
Decision making |
en |
| dc.subject.other |
Discriminant analysis |
en |
| dc.subject.other |
Herbicides |
en |
| dc.subject.other |
Metabolism |
en |
| dc.subject.other |
Multivariant analysis |
en |
| dc.subject.other |
Nuclear magnetic resonance |
en |
| dc.subject.other |
Nuclear magnetic resonance spectroscopy |
en |
| dc.subject.other |
Risk management |
en |
| dc.subject.other |
Risk assessment |
en |
| dc.subject.other |
glyphosate |
en |
| dc.subject.other |
herbicide |
en |
| dc.subject.other |
mesotrione |
en |
| dc.subject.other |
norflurazon |
en |
| dc.subject.other |
paraquat |
en |
| dc.subject.other |
pyrenophorol |
en |
| dc.subject.other |
unclassified drug |
en |
| dc.subject.other |
xenobiotic agent |
en |
| dc.subject.other |
cluster analysis |
en |
| dc.subject.other |
discriminant analysis |
en |
| dc.subject.other |
DNA fingerprinting |
en |
| dc.subject.other |
ecotoxicology |
en |
| dc.subject.other |
least squares method |
en |
| dc.subject.other |
metabolism |
en |
| dc.subject.other |
microorganism |
en |
| dc.subject.other |
multivariate analysis |
en |
| dc.subject.other |
nuclear magnetic resonance |
en |
| dc.subject.other |
phytotoxicity |
en |
| dc.subject.other |
risk assessment |
en |
| dc.subject.other |
toxin |
en |
| dc.subject.other |
weed |
en |
| dc.subject.other |
xenobiotics |
en |
| dc.subject.other |
article |
en |
| dc.subject.other |
bioassay |
en |
| dc.subject.other |
cluster analysis |
en |
| dc.subject.other |
controlled study |
en |
| dc.subject.other |
discriminant analysis |
en |
| dc.subject.other |
ecotoxicology |
en |
| dc.subject.other |
lemna minor |
en |
| dc.subject.other |
macrophyte |
en |
| dc.subject.other |
metabolomics |
en |
| dc.subject.other |
nonhuman |
en |
| dc.subject.other |
partial least squares regression |
en |
| dc.subject.other |
phytotoxicity |
en |
| dc.subject.other |
proton nuclear magnetic resonance |
en |
| dc.subject.other |
risk assessment |
en |
| dc.subject.other |
Araceae |
en |
| dc.subject.other |
Cluster Analysis |
en |
| dc.subject.other |
Discriminant Analysis |
en |
| dc.subject.other |
Ecotoxicology |
en |
| dc.subject.other |
Herbicides |
en |
| dc.subject.other |
Least-Squares Analysis |
en |
| dc.subject.other |
Magnetic Resonance Spectroscopy |
en |
| dc.subject.other |
Metabolomics |
en |
| dc.subject.other |
Principal Component Analysis |
en |
| dc.subject.other |
Xenobiotics |
en |
| dc.subject.other |
Lemna |
en |
| dc.subject.other |
Lemna minor |
en |
| dc.title |
Lemna minor L. as a model organism for ecotoxicological studies performing 1H NMR fingerprinting |
en |
| heal.type |
journalArticle |
en |
| heal.identifier.primary |
10.1016/j.chemosphere.2009.04.025 |
en |
| heal.publicationDate |
2009 |
en |
| heal.abstract |
A validated method applying 1H NMR fingerprinting for the study of metabolic changes caused in Lemna minor L. by various phytotoxic substances is presented. 1H NMR spectra of crude extracts from untreated and treated colonies with the herbicides glyphosate, mesotrione, norflurazon, paraquat and the phytotoxin pyrenophorol were subjected to multivariate analyses for detecting differences between groups of treatments. Partial least squares-discriminant analysis (PLS-DA) and hierarchical cluster analysis (HCA) were carried out in order to discriminate and classify treatments according to the observed changes in the metabolome of the plant. Although the compounds at the concentrations used did not cause macroscopically observable symptoms of phytotoxicity, characteristic metabolic changes were detectable by analyzing 1H NMR spectra. Analyses results revealed that metabonomics applying 1H NMR fingerprinting is a potential method for the investigation of toxicological effects of xenobiotics on L. minor, and possibly on other duckweed species, helping in the understanding of such interactions. © 2009 Elsevier Ltd. All rights reserved. |
en |
| heal.journalName |
Chemosphere |
en |
| dc.identifier.issue |
7 |
en |
| dc.identifier.volume |
76 |
en |
| dc.identifier.doi |
10.1016/j.chemosphere.2009.04.025 |
en |
| dc.identifier.spage |
967 |
en |
| dc.identifier.epage |
973 |
en |