Functional evolution of cyclin-dependent kinases

dc.contributor.author	Doonan, JH	en
dc.contributor.author	Kitsios, G	en
dc.date.accessioned	2014-06-06T06:49:24Z
dc.date.available	2014-06-06T06:49:24Z
dc.date.issued	2009	en
dc.identifier.issn	10736085	en
dc.identifier.uri	http://dx.doi.org/10.1007/s12033-008-9126-8	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/4580
dc.subject	Animal	en
dc.subject	Cell cycle	en
dc.subject	Cyclin-dependent kinases	en
dc.subject	Gene expression	en
dc.subject	Plant	en
dc.subject	Yeast	en
dc.subject.other	Animal cells	en
dc.subject.other	Biological process	en
dc.subject.other	CDK phosphorylation	en
dc.subject.other	Cell cycle	en
dc.subject.other	Cellular process	en
dc.subject.other	Cyclin-dependent kinase	en
dc.subject.other	Cyclin-dependent kinases	en
dc.subject.other	Eukaryotic cell cycle	en
dc.subject.other	Gene families	en
dc.subject.other	In-plants	en
dc.subject.other	Plant	en
dc.subject.other	Protein kinase	en
dc.subject.other	Bioactivity	en
dc.subject.other	Transcription	en
dc.subject.other	Yeast	en
dc.subject.other	Animals	en
dc.subject.other	cyclin dependent kinase	en
dc.subject.other	cyclin dependent kinase 7	en
dc.subject.other	cyclin dependent kinase 8	en
dc.subject.other	cyclin dependent kinase 9	en
dc.subject.other	RNA	en
dc.subject.other	RNA polymerase II	en
dc.subject.other	animal	en
dc.subject.other	carboxy terminal sequence	en
dc.subject.other	cell cycle G1 phase	en
dc.subject.other	cell cycle M phase	en
dc.subject.other	cell cycle regulation	en
dc.subject.other	cell cycle S phase	en
dc.subject.other	chromatin structure	en
dc.subject.other	enzyme activity	en
dc.subject.other	enzyme phosphorylation	en
dc.subject.other	functional proteomics	en
dc.subject.other	gene expression	en
dc.subject.other	gene expression regulation	en
dc.subject.other	molecular evolution	en
dc.subject.other	multigene family	en
dc.subject.other	nonhuman	en
dc.subject.other	plant	en
dc.subject.other	protein function	en
dc.subject.other	protein phosphorylation	en
dc.subject.other	review	en
dc.subject.other	RNA splicing	en
dc.subject.other	RNA translation	en
dc.subject.other	transcription regulation	en
dc.subject.other	yeast	en
dc.subject.other	cell cycle	en
dc.subject.other	genetic transcription	en
dc.subject.other	genetics	en
dc.subject.other	human	en
dc.subject.other	phylogeny	en
dc.subject.other	physiology	en
dc.subject.other	protein synthesis	en
dc.subject.other	Animalia	en
dc.subject.other	Eukaryota	en
dc.subject.other	Animals	en
dc.subject.other	Cell Cycle	en
dc.subject.other	Cyclin-Dependent Kinases	en
dc.subject.other	Evolution, Molecular	en
dc.subject.other	Gene Expression	en
dc.subject.other	Gene Expression Regulation	en
dc.subject.other	Humans	en
dc.subject.other	Phylogeny	en
dc.subject.other	Plants	en
dc.subject.other	Protein Biosynthesis	en
dc.subject.other	RNA Splicing	en
dc.subject.other	Transcription, Genetic	en
dc.subject.other	Yeasts	en
dc.title	Functional evolution of cyclin-dependent kinases	en
heal.type	other	en
heal.identifier.primary	10.1007/s12033-008-9126-8	en
heal.publicationDate	2009	en
heal.abstract	Cyclin-dependent kinases (CDKs) are serine/threonine protein kinases with a well established role in the regulation of the eukaryotic cell cycle. Recent studies with animal cells have implicated CDK activity in additional diverse cellular processes, including transcription, translation and mRNA processing. In plants, such CDK functions are poorly characterized and the implication of CDK phosphorylation in regulation of gene expression is just begining to emerge. In this review we compare CDK functions in plants, animals and yeasts with particular focus on the biological processes that different members participate in and regulate. Finally, based on the available information of CDK function, we propose an alternative evolutionary scenario for the CDK gene family. © 2009 Humana Press.	en
heal.journalName	Molecular Biotechnology	en
dc.identifier.issue	1	en
dc.identifier.volume	42	en
dc.identifier.doi	10.1007/s12033-008-9126-8	en
dc.identifier.spage	14	en
dc.identifier.epage	29	en