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Susceptibility to peroxidation of the major mycelial lipids of Cunninghamella echinulata

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dc.contributor.author Fakas, S en
dc.contributor.author Papapostolou, I en
dc.contributor.author Papanikolaou, S en
dc.contributor.author Georgiou, CD en
dc.contributor.author Aggelis, G en
dc.date.accessioned 2014-06-06T06:48:42Z
dc.date.available 2014-06-06T06:48:42Z
dc.date.issued 2008 en
dc.identifier.issn 14387697 en
dc.identifier.uri http://dx.doi.org/10.1002/ejlt.200800025 en
dc.identifier.uri http://62.217.125.90/xmlui/handle/123456789/4244
dc.subject Cunninghamella echinulata en
dc.subject Glycolipids plus sphingolipids en
dc.subject Lipid hydroperoxides en
dc.subject Neutral lipids en
dc.subject Peroxidation en
dc.subject Phospholipids en
dc.subject Specific lipid peroxidizability en
dc.subject.other Cunninghamella echinulata en
dc.subject.other Fungi en
dc.title Susceptibility to peroxidation of the major mycelial lipids of Cunninghamella echinulata en
heal.type journalArticle en
heal.identifier.primary 10.1002/ejlt.200800025 en
heal.publicationDate 2008 en
heal.abstract The distribution of hydroperoxides among lipid fractions (namely neutral lipids, glycolipids, sphingolipids, and phospholipids) of the oleaginous fungus Cunninghamella echinulata was studied during the growth cycle. The lipid hydroperoxide content of total lipids increased during growth. Neutral lipids contained a small amount of hydroperoxides (0.78 × 10-4-5 × 10-4 μmol/mg), glycolipids plus sphingolipids contained large amounts of hydroperoxides (14 × 10-4-17.6 × 10 -4 μmol/mg), while the hydroperoxide content of phospholipids increased greatly during growth (from 4.6 × 10-4 to 38 × 10-4 μmol/mg). In addition, the distribution of lipid hydroperoxides among the major phospholipid classes indicated that the neutral phospholipids, namely phosphatidylcholine and phosphatidylethanolamine, were more susceptible to peroxidation than the anionic ones (i.e. phosphatidylinositol and phosphatidylserine). A novel parameter, namely ""specific lipid peroxidizability"", which is able to evaluate the susceptibility to peroxidation (peroxidizability) of each lipid fraction/class due to the nature of the lipid itself, was introduced. By using this parameter it was found that peroxidizability depended on the nature of the individual lipid rather than on its polyunsaturated fatty acid content. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA. en
heal.journalName European Journal of Lipid Science and Technology en
dc.identifier.issue 11 en
dc.identifier.volume 110 en
dc.identifier.doi 10.1002/ejlt.200800025 en
dc.identifier.spage 1062 en
dc.identifier.epage 1067 en


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