| dc.contributor.author |
Sarikurkcu, C |
en |
| dc.contributor.author |
Tepe, B |
en |
| dc.contributor.author |
Daferera, D |
en |
| dc.contributor.author |
Polissiou, M |
en |
| dc.contributor.author |
Harmandar, M |
en |
| dc.date.accessioned |
2014-06-06T06:48:41Z |
|
| dc.date.available |
2014-06-06T06:48:41Z |
|
| dc.date.issued |
2008 |
en |
| dc.identifier.issn |
09608524 |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1016/j.biortech.2007.08.058 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/4238 |
|
| dc.subject |
β-carotene |
en |
| dc.subject |
Antioxidant activity |
en |
| dc.subject |
DPPH |
en |
| dc.subject |
Marrubium globosum subsp. globosum |
en |
| dc.subject |
Reducing power |
en |
| dc.subject.other |
Enzyme inhibition |
en |
| dc.subject.other |
Extraction |
en |
| dc.subject.other |
Methanol |
en |
| dc.subject.other |
Scavenging |
en |
| dc.subject.other |
Antioxidant activity |
en |
| dc.subject.other |
Marrubium globosum subsp. globosum |
en |
| dc.subject.other |
Reducing power |
en |
| dc.subject.other |
Enzyme activity |
en |
| dc.subject.other |
1,1 diphenyl 2 picrylhydrazyl |
en |
| dc.subject.other |
antioxidant |
en |
| dc.subject.other |
beta carotene |
en |
| dc.subject.other |
bicyclogermacrene |
en |
| dc.subject.other |
caryophyllene |
en |
| dc.subject.other |
caryophyllene oxide |
en |
| dc.subject.other |
essential oil |
en |
| dc.subject.other |
germacrene D |
en |
| dc.subject.other |
linoleic acid |
en |
| dc.subject.other |
phenol derivative |
en |
| dc.subject.other |
spathulenol |
en |
| dc.subject.other |
Enzyme activity |
en |
| dc.subject.other |
Enzyme inhibition |
en |
| dc.subject.other |
Extraction |
en |
| dc.subject.other |
Methanol |
en |
| dc.subject.other |
Scavenging |
en |
| dc.subject.other |
antioxidant |
en |
| dc.subject.other |
carotenoid |
en |
| dc.subject.other |
enzyme activity |
en |
| dc.subject.other |
essential oil |
en |
| dc.subject.other |
gas chromatography |
en |
| dc.subject.other |
herb |
en |
| dc.subject.other |
inhibition |
en |
| dc.subject.other |
methanol |
en |
| dc.subject.other |
antioxidant activity |
en |
| dc.subject.other |
article |
en |
| dc.subject.other |
drug isolation |
en |
| dc.subject.other |
gas chromatography |
en |
| dc.subject.other |
Marrubium globosum |
en |
| dc.subject.other |
mass spectrometry |
en |
| dc.subject.other |
medicinal plant |
en |
| dc.subject.other |
phytochemistry |
en |
| dc.subject.other |
priority journal |
en |
| dc.subject.other |
Antioxidants |
en |
| dc.subject.other |
beta Carotene |
en |
| dc.subject.other |
Biotechnology |
en |
| dc.subject.other |
Biphenyl Compounds |
en |
| dc.subject.other |
Chromatography, Gas |
en |
| dc.subject.other |
Flavonoids |
en |
| dc.subject.other |
Gas Chromatography-Mass Spectrometry |
en |
| dc.subject.other |
Hydrazines |
en |
| dc.subject.other |
Lamiaceae |
en |
| dc.subject.other |
Linoleic Acid |
en |
| dc.subject.other |
Marrubium |
en |
| dc.subject.other |
Methanol |
en |
| dc.subject.other |
Oils, Volatile |
en |
| dc.subject.other |
Phenol |
en |
| dc.subject.other |
Plant Extracts |
en |
| dc.subject.other |
Lamiaceae |
en |
| dc.subject.other |
Marrubium |
en |
| dc.title |
Studies on the antioxidant activity of the essential oil and methanol extract of Marrubium globosum subsp. globosum (lamiaceae) by three different chemical assays |
en |
| heal.type |
journalArticle |
en |
| heal.identifier.primary |
10.1016/j.biortech.2007.08.058 |
en |
| heal.publicationDate |
2008 |
en |
| heal.abstract |
This study is designed to examine the chemical composition and in vitro antioxidant activity of the essential oil and sub-fractions of the methanol extract of Marrubium globosum subsp. globosum. The GC and GC-MS analysis of the essential oil were resulted in the determination of 84 components representing 88.2% of the oil. The major constituents of the oil were spathulenol (15.8%), β-caryophyllene (9.0%), caryophyllene oxide (7.9%), germacrene D (6.5%), and bicyclogermacrene (3.1%). Antioxidant activities of the samples were determined by three different test systems namely DPPH, β-carotene/linoleic acid and reducing power assay. In DPPH system, the weakest radical scavenging activity was exhibited by the essential oil (1203.38 ± 7.18 μg ml-1). Antioxidant activity of the polar sub-fraction of methanol extract was superior to the all samples tested with an EC50 value of 157.26 ± 1.12 μg ml-1. In the second case, the inhibition capacity (%) of the polar sub-fraction of methanol extract (97.39% ± 0.84) was found the strongest one, which is almost equal to the inhibition capacity of positive control BHT (97.44% ± 0.74). In the case of reducing power assay, a similar activity pattern was observed as given in the first two systems. Polar sub-fraction was the strongest radical reducer when compared with the non-polar one, with an EC50 value of 625.63 ± 1.02 μg ml-1. The amount of the total phenolics was highest in polar sub-fraction (25.60 ± 0.74 μg/mg). A positive correlation was observed between the antioxidant activity potential and total phenolic level of the extracts. On the other hand, total flavonoid content was found equal for the both sub-fractions. © 2007 Elsevier Ltd. All rights reserved. |
en |
| heal.journalName |
Bioresource Technology |
en |
| dc.identifier.issue |
10 |
en |
| dc.identifier.volume |
99 |
en |
| dc.identifier.doi |
10.1016/j.biortech.2007.08.058 |
en |
| dc.identifier.spage |
4239 |
en |
| dc.identifier.epage |
4246 |
en |