Synthetic Bastadins Modify the Activity of Ryanodine Receptors in Cultured Cerebellar Granule Cells

dc.contributor.author	Zieminska, E	en
dc.contributor.author	Stafiej, A	en
dc.contributor.author	Pitsinos, E	en
dc.contributor.author	Couladouros, E	en
dc.contributor.author	Moutsos, V	en
dc.contributor.author	Kozlowska, H	en
dc.contributor.author	Toczylowska, B	en
dc.contributor.author	Lazarewicz, J	en
dc.date.accessioned	2014-06-06T06:48:18Z
dc.date.available	2014-06-06T06:48:18Z
dc.date.issued	2008	en
dc.identifier.uri	http://dx.doi.org/10.1159/000107650	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/4088
dc.subject	Calcium Transient	en
dc.subject	Cardiac Muscle	en
dc.subject	Cerebellar Granule Cell	en
dc.subject	Confocal Microscopy	en
dc.subject	intracellular ca2+	en
dc.subject	Primary Culture	en
dc.subject	Ryanodine Receptor	en
dc.subject	Sarcoplasmic Reticulum	en
dc.title	Synthetic Bastadins Modify the Activity of Ryanodine Receptors in Cultured Cerebellar Granule Cells	en
heal.type	journalArticle	en
heal.identifier.primary	10.1159/000107650	en
heal.publicationDate	2008	en
heal.abstract	Although the interactions of several natural bastadins with the RyR1 isoform of the ryanodine receptor in sarcoplasmic reticulum has been described, their structure-dependent interference with the RyR2 isoform, mainly expressed in cardiac muscle and brain neurons, has not been studied. In this work, we examined calcium transients induced by natural bastadin 10 and several synthetic bastadins in cultured cerebellar granule	en
heal.journalName	Neurosignals	en
dc.identifier.doi	10.1159/000107650	en