| dc.contributor.author |
Beopoulos, A |
en |
| dc.contributor.author |
Mrozova, Z |
en |
| dc.contributor.author |
Dall, M |
en |
| dc.contributor.author |
Hapala, I |
en |
| dc.contributor.author |
Papanikolaou, S |
en |
| dc.contributor.author |
Chardot, T |
en |
| dc.contributor.author |
Nicaud, J |
en |
| dc.date.accessioned |
2014-06-06T06:48:16Z |
|
| dc.date.available |
2014-06-06T06:48:16Z |
|
| dc.date.issued |
2008 |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1128/AEM.01412-08 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/4051 |
|
| dc.subject |
Carbon Flux |
en |
| dc.subject |
Genome Comparison |
en |
| dc.subject |
saccharomyces cerevisiae |
en |
| dc.subject |
yarrowia lipolytica |
en |
| dc.subject |
glycerol 3 phosphate |
en |
| dc.subject |
Wild Type |
en |
| dc.title |
Control of Lipid Accumulation in the Yeast Yarrowia lipolytica |
en |
| heal.type |
journalArticle |
en |
| heal.identifier.primary |
10.1128/AEM.01412-08 |
en |
| heal.publicationDate |
2008 |
en |
| heal.abstract |
A genomic comparison of Yarrowia lipolytica and Saccharomyces cerevisiae indicates that the metabolism of Y. lipolytica is oriented toward the glycerol pathway. To redirect carbon flux toward lipid synthesis, the GUT2 gene, which codes for the glycerol-3-phosphate dehydrogenase isomer, was deleted in Y. lipolytica in this study. This gut2 mutant strain demonstrated a threefold increase in lipid accumulation compared to |
en |
| heal.journalName |
Applied and Environmental Microbiology |
en |
| dc.identifier.doi |
10.1128/AEM.01412-08 |
en |