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Studies on bacteriocin (thermophilin T) production by Streptococcus thermophilus ACA-DC 0040 in batch and fed-batch fermentation modes

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dc.contributor.author Aktypis, A en
dc.contributor.author Tychowski, M en
dc.contributor.author Kalantzopoulos, G en
dc.contributor.author Aggelis, G en
dc.date.accessioned 2014-06-06T06:48:02Z
dc.date.available 2014-06-06T06:48:02Z
dc.date.issued 2007 en
dc.identifier.issn 00036072 en
dc.identifier.uri http://dx.doi.org/10.1007/s10482-007-9148-4 en
dc.identifier.uri http://62.217.125.90/xmlui/handle/123456789/3924
dc.subject Batch and Fed-batch fermentation en
dc.subject LAB bacteriocins en
dc.subject Modelling en
dc.subject Streptococcus thermophilus en
dc.subject Thermophilin T production en
dc.subject.other bacteriocin en
dc.subject.other nitrogen en
dc.subject.other article en
dc.subject.other bacterial growth en
dc.subject.other bacterial strain en
dc.subject.other batch fermentation en
dc.subject.other controlled study en
dc.subject.other culture medium en
dc.subject.other fed batch fermentation en
dc.subject.other nonhuman en
dc.subject.other priority journal en
dc.subject.other Streptococcus thermophilus en
dc.subject.other synthesis en
dc.subject.other temperature en
dc.subject.other Bacteriocins en
dc.subject.other Bioreactors en
dc.subject.other Fermentation en
dc.subject.other Glucose en
dc.subject.other Nitrogen en
dc.subject.other Streptococcus thermophilus en
dc.subject.other Time Factors en
dc.subject.other Streptococcus thermophilus en
dc.title Studies on bacteriocin (thermophilin T) production by Streptococcus thermophilus ACA-DC 0040 in batch and fed-batch fermentation modes en
heal.type journalArticle en
heal.identifier.primary 10.1007/s10482-007-9148-4 en
heal.publicationDate 2007 en
heal.abstract Growth conditions that support bacteriocin (thermophilin T) production by Streptococcus thermophilus ACA-DC 0040 were identified. Synthesis of thermophilin T occurred during primary metabolic growth, while its specific rate of synthesis seemed to be optimal at T = 30°C. Thermophilin T activity rapidly decreased in the stationary phase, especially at high growth temperature (i.e. T = 42°C). In media with high content of complex nitrogen sources, high amounts of bacteriocin were detected in the growth environment, while about an 8-fold increase of thermophilin T titer and a 2-fold increase of specific synthesis rate was achieved when a fed-batch fermentation mode was applied. © Springer Science+Business Media B.V. 2007. en
heal.journalName Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology en
dc.identifier.issue 2 en
dc.identifier.volume 92 en
dc.identifier.doi 10.1007/s10482-007-9148-4 en
dc.identifier.spage 207 en
dc.identifier.epage 220 en


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