Synthesis of (R)-dihydropyridones as key intermediates for an efficient access to piperidine alkaloids

dc.contributor.advisor	Haroutounian, Serkos A.	en
dc.contributor.advisor	Χαρουτουνιάν, Σέρκος Α.	el
dc.contributor.author	Tzanetou, Evangelia N.	en
dc.contributor.author	Kasiotis, Konstantinos M.	en
dc.contributor.author	Magiatis, Prokopios	en
dc.contributor.author	Τζανέτου, Ευαγγελία Ν.	el
dc.contributor.author	Κασιώτης, Κωνσταντίνος Μ.	el
dc.contributor.author	Μαγιάτης, Προκόπιος	el
dc.date.accessioned	2014-06-06T06:47:57Z
dc.date.available	2014-06-06T06:47:57Z
dc.date.issued	2007-04-10	en
dc.identifier.issn	14203049	en
dc.identifier.uri	http://dx.doi.org/10.3390/12040735	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/3882
dc.rights	CC0 1.0 Παγκόσμια	en
dc.rights.uri	http://creativecommons.org/publicdomain/zero/1.0/	en
dc.title	Synthesis of (R)-dihydropyridones as key intermediates for an efficient access to piperidine alkaloids	en
heal.type	journalArticle	en
heal.keyword	Asymmetric synthesis	en
heal.keyword	Azasugars	en
heal.keyword	Dihydropyridones	en
heal.keyword	Piperidine alkaloids	en
heal.keyword	Carbohydrate	en
heal.keyword	Stereoisomerism	en
heal.keyword	Catalysis	en
heal.keyword	Ethanol	en
heal.keyword	Molecular Structure	en
heal.identifier.primary	10.3390/12040735	en
heal.recordProvider	Πανεπιστήμιο Αθηνών/Τμήμα Φαρμακευτικής	el
heal.recordProvider	Γεωπονικό Πανεπιστήμιο Αθηνών/Γενικό Τμήμα	el
heal.publicationDate	2007-04-10	en
heal.bibliographicCitation	Haroutounian, Serkos A. Synthesis of (R)-dihydropyridones as key intermediates for an efficient access to piperidine alkaloids. Molecules, vol. 12 (4), pp. 735-744, MDPI 2007	en
heal.abstract	The efficient transformation of D-glucal to (2R)- hydroxymethyldihydropyridinone 5 in seven steps and 35 % overall yield is reported. Dihydropyridone 5 constitutes a versatile chiral building block for the synthesis of various piperidine alkaloids. In this regard, 5 was converted to piperidinol 13 and piperidinone 15, that may be further elaborated for the syntheses of (+)-desoxoprosophylline (1) and deoxymannojirimycin (3) or D-mannolactam (4), respectively.	en
heal.publisher	Molecular Diversity Preservation International (MDPI)	en
heal.journalName	Molecules	en
dc.identifier.doi	10.3390/12040735	en