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Oestradiol concentration as a predictor of ovarian response in FSH stimulated ewe-lambs

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dc.contributor.author Valasi, I en
dc.contributor.author Leontides, L en
dc.contributor.author Menegatos, I en
dc.contributor.author Amiridis, GS en
dc.date.accessioned 2014-06-06T06:47:54Z
dc.date.available 2014-06-06T06:47:54Z
dc.date.issued 2007 en
dc.identifier.issn 03784320 en
dc.identifier.uri http://dx.doi.org/10.1016/j.anireprosci.2007.02.006 en
dc.identifier.uri http://62.217.125.90/xmlui/handle/123456789/3847
dc.subject Ewe-lambs en
dc.subject FSH en
dc.subject Oestradiol en
dc.subject Oocytes pick-up en
dc.subject Superovulation en
dc.subject.other estradiol en
dc.subject.other fertility promoting agent en
dc.subject.other follitropin en
dc.subject.other progesterone en
dc.subject.other animal en
dc.subject.other article en
dc.subject.other blood en
dc.subject.other clinical trial en
dc.subject.other controlled clinical trial en
dc.subject.other controlled study en
dc.subject.other drug effect en
dc.subject.other female en
dc.subject.other ovary en
dc.subject.other physiology en
dc.subject.other sexual maturation en
dc.subject.other sheep en
dc.subject.other Animals en
dc.subject.other Estradiol en
dc.subject.other Female en
dc.subject.other Fertility Agents, Female en
dc.subject.other Follicle Stimulating Hormone en
dc.subject.other Ovary en
dc.subject.other Progesterone en
dc.subject.other Sexual Maturation en
dc.subject.other Sheep en
dc.subject.other Animalia en
dc.subject.other Ovis aries en
dc.title Oestradiol concentration as a predictor of ovarian response in FSH stimulated ewe-lambs en
heal.type journalArticle en
heal.identifier.primary 10.1016/j.anireprosci.2007.02.006 en
heal.publicationDate 2007 en
heal.abstract We investigated the prediction of ovarian response using oestradiol determination, in 37 gonadotrophin stimulated Karagouniko ewe-lambs. Ovarian stimulation was induced by serial FSH administrations, and laparoscopic follicular aspiration (OPU) was conducted 12 h after the last FSH injection. Oestradiol concentration was assessed in six blood samples collected prior to each FSH injection and in one sample collected prior to follicular aspiration. According to ovarian response, ewe-lambs were allotted in three groups: good, L1 (n = 17); moderate, L2 (n = 10); and poor, L3 (n = 10). Based on the data obtained from 28 (75%) randomly selected animals, a statistical model was designed and tested on the remaining nine lambs for its ability to predict the probability of good ovarian response. From the 2nd sample, oestradiol concentration was constantly higher in group L1 in comparison with L3 lambs (all p-values for the contrasts were ≤0.02), while this difference between L1 and L2 lambs was significant only in the 6th and 7th sample (both p < 0.005). Using as criterion the oestradiol concentration of the 6th sample, the statistical model predicted all lambs that did not belong to group L1 and three of four lambs that belonged to group L1. Our results indicate that the moderate- and poor-donors could be safely predicted on the basis of oestradiol concentration 12 h prior to the scheduled follicular aspiration. Moreover, poor-donors could be identified-and rejected from further manipulations-on the basis of their inability to exhibit increased oestradiol levels in response to gonadotrophin stimulus. © 2007 Elsevier B.V. All rights reserved. en
heal.journalName Animal Reproduction Science en
dc.identifier.issue 1-2 en
dc.identifier.volume 102 en
dc.identifier.doi 10.1016/j.anireprosci.2007.02.006 en
dc.identifier.spage 145 en
dc.identifier.epage 151 en


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