Identification of conserved secondary structures and expansion segments in enod40 RNAs reveals new enod40 homologues in plants

dc.contributor.author	Gultyaev, AP	en
dc.contributor.author	Roussis, A	en
dc.date.accessioned	2014-06-06T06:47:47Z
dc.date.available	2014-06-06T06:47:47Z
dc.date.issued	2007	en
dc.identifier.issn	03051048	en
dc.identifier.uri	http://dx.doi.org/10.1093/nar/gkm173	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/3805
dc.subject.other	peptide derivative	en
dc.subject.other	plant RNA	en
dc.subject.other	protein ENOD40	en
dc.subject.other	ribonuclease P	en
dc.subject.other	ribosome RNA	en
dc.subject.other	unclassified drug	en
dc.subject.other	vegetable protein	en
dc.subject.other	ENOD40 RNA	en
dc.subject.other	untranslated RNA	en
dc.subject.other	article	en
dc.subject.other	controlled study	en
dc.subject.other	gene function	en
dc.subject.other	gene identification	en
dc.subject.other	genetic code	en
dc.subject.other	genetic conservation	en
dc.subject.other	genetic database	en
dc.subject.other	molecular evolution	en
dc.subject.other	molecular mechanics	en
dc.subject.other	nucleotide sequence	en
dc.subject.other	plant genetics	en
dc.subject.other	prediction	en
dc.subject.other	priority journal	en
dc.subject.other	protein determination	en
dc.subject.other	protein domain	en
dc.subject.other	protein secondary structure	en
dc.subject.other	RNA analysis	en
dc.subject.other	RNA sequence	en
dc.subject.other	RNA structure	en
dc.subject.other	sequence homology	en
dc.subject.other	structure analysis	en
dc.subject.other	chemistry	en
dc.subject.other	conformation	en
dc.subject.other	nucleic acid database	en
dc.subject.other	sequence analysis	en
dc.subject.other	Embryophyta	en
dc.subject.other	Fabaceae	en
dc.subject.other	Fungi	en
dc.subject.other	Databases, Nucleic Acid	en
dc.subject.other	Evolution, Molecular	en
dc.subject.other	Nucleic Acid Conformation	en
dc.subject.other	RNA, Plant	en
dc.subject.other	RNA, Untranslated	en
dc.subject.other	Sequence Analysis, RNA	en
dc.subject.other	Sequence Homology, Nucleic Acid	en
dc.title	Identification of conserved secondary structures and expansion segments in enod40 RNAs reveals new enod40 homologues in plants	en
heal.type	journalArticle	en
heal.identifier.primary	10.1093/nar/gkm173	en
heal.publicationDate	2007	en
heal.abstract	enod40 is a plant gene that participates in the regulation of symbiotic interaction between leguminous plants and bacteria or fungi. Furthermore, it has been suggested to play a general role in nonsymbiotic plant development. Although enod40 seems to have multiple functions, being present in many land plants, the molecular mechanisms of its activity are unclear; they may be determined though, by short peptides and/or RNA structures encoded in the enod40 genes. We utilized conserved RNA structures in enod40 sequences to search nucleotide sequence databases and identified a number of new enod40 homologues in plant species that belong to known, but also, to yet unknown enod40-containing plant families. RNA secondary structure predictions and comparative sequence analysis of enod40 RNAs allowed us to determine the most conserved structural features, present in all known enod40 genes. Remarkably, the topology and evolution of one of the conserved structural domains are similar to those of the expansion segments found in structural RNAs such as rRNAs, RNase P and SRP RNAs. Surprisingly, the enod40 RNA structural elements are much more stronger conserved than the encoded peptides. This finding suggests that some general functions of enod40 gene could be determined by the encoded RNA structure, whereas short peptides may be responsible for more diverse functions found only in certain plant families. © 2007 The Author(s).	en
heal.journalName	Nucleic Acids Research	en
dc.identifier.issue	9	en
dc.identifier.volume	35	en
dc.identifier.doi	10.1093/nar/gkm173	en
dc.identifier.spage	3144	en
dc.identifier.epage	3152	en