Enzymatic removal of carboxyl protecting groups. III. Fast removal of allyl and chloroethyl esters by Bacillus subtilis esterase (BS2)

dc.contributor.author	Fotakopoulou, I	en
dc.contributor.author	Barbayianni, E	en
dc.contributor.author	Constantinou-Kokotou, V	en
dc.contributor.author	Bornscheuer, UT	en
dc.contributor.author	Kokotos, G	en
dc.date.accessioned	2014-06-06T06:47:43Z
dc.date.available	2014-06-06T06:47:43Z
dc.date.issued	2007	en
dc.identifier.issn	00223263	en
dc.identifier.uri	http://dx.doi.org/10.1021/jo061871f	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/3774
dc.subject.other	Bacteria	en
dc.subject.other	Enzyme kinetics	en
dc.subject.other	Enzymes	en
dc.subject.other	Hydrolysis	en
dc.subject.other	Removal	en
dc.subject.other	Chloroethyl esters	en
dc.subject.other	Esterases	en
dc.subject.other	Hydrolyzes	en
dc.subject.other	Phenacyl esters	en
dc.subject.other	Esters	en
dc.subject.other	allyl compound	en
dc.subject.other	bacterial enzyme	en
dc.subject.other	ester	en
dc.subject.other	ester derivative	en
dc.subject.other	esterase	en
dc.subject.other	article	en
dc.subject.other	Bacillus subtilis	en
dc.subject.other	chemical reaction	en
dc.subject.other	enzyme activity	en
dc.subject.other	enzyme analysis	en
dc.subject.other	enzyme substrate	en
dc.subject.other	hydrolysis	en
dc.subject.other	nonhuman	en
dc.subject.other	Allyl Compounds	en
dc.subject.other	Bacillus subtilis	en
dc.subject.other	Carboxylic Acids	en
dc.subject.other	Esterases	en
dc.subject.other	Esters	en
dc.subject.other	Ethyl Chloride	en
dc.subject.other	Hydrolysis	en
dc.subject.other	Models, Chemical	en
dc.subject.other	Time Factors	en
dc.title	Enzymatic removal of carboxyl protecting groups. III. Fast removal of allyl and chloroethyl esters by Bacillus subtilis esterase (BS2)	en
heal.type	journalArticle	en
heal.identifier.primary	10.1021/jo061871f	en
heal.publicationDate	2007	en
heal.abstract	(Chemical Equation Presented) An esterase from Bacillus subtilis (BS2) allows the fast and selective removal of allyl, 2-chloroethyl, and 2,2,2-chloroethyl esters under mild conditions in high yields. In addition, BS2 easily hydrolyzes phenacyl esters, while the hydrolysis of sterically hindered diphenylmethyl esters is slow, requiring longer reaction time and higher enzyme/substrate ratio. © 2007 American Chemical Society.	en
heal.journalName	Journal of Organic Chemistry	en
dc.identifier.issue	3	en
dc.identifier.volume	72	en
dc.identifier.doi	10.1021/jo061871f	en
dc.identifier.spage	782	en
dc.identifier.epage	786	en