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Chemical composition and antioxidant activity of the essential oil of Clinopodium vulgare L.

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dc.contributor.author Tepe, B en
dc.contributor.author Sihoglu-Tepe, A en
dc.contributor.author Daferera, D en
dc.contributor.author Polissiou, M en
dc.contributor.author Sokmen, A en
dc.date.accessioned 2014-06-06T06:47:38Z
dc.date.available 2014-06-06T06:47:38Z
dc.date.issued 2007 en
dc.identifier.issn 03088146 en
dc.identifier.uri http://dx.doi.org/10.1016/j.foodchem.2006.09.019 en
dc.identifier.uri http://62.217.125.90/xmlui/handle/123456789/3725
dc.subject Antioxidant activity en
dc.subject Clinopodium vulgare en
dc.subject Essential oil en
dc.subject.other 1,1 diphenyl 2 picrylhydrazyl en
dc.subject.other antioxidant en
dc.subject.other ascorbic acid en
dc.subject.other beta carotene en
dc.subject.other butylcresol en
dc.subject.other curcumin en
dc.subject.other essential oil en
dc.subject.other linoleic acid en
dc.subject.other para cymene en
dc.subject.other terpinene en
dc.subject.other thymol en
dc.subject.other antioxidant activity en
dc.subject.other article en
dc.subject.other assay en
dc.subject.other chemical analysis en
dc.subject.other chemical composition en
dc.subject.other Clinopodium vulgare en
dc.subject.other gas chromatography en
dc.subject.other IC 50 en
dc.subject.other mass spectrometer en
dc.subject.other oxidation en
dc.subject.other plant en
dc.subject.other Clinopodium vulgare en
dc.title Chemical composition and antioxidant activity of the essential oil of Clinopodium vulgare L. en
heal.type journalArticle en
heal.identifier.primary 10.1016/j.foodchem.2006.09.019 en
heal.publicationDate 2007 en
heal.abstract This study was designed to examine the chemical composition and in vitro antioxidant activity of the essential oil of Clinopodium vulgare. GC-MS analysis of the oil resulted in the identification of 40 compounds, representing 99.4% of the oil; thymol (38.9%), γ-terpinene (29.6%) and p-cymene (9.1%) were the main components. The samples were subjected to a screening for their possible antioxidant activity by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and β-carotene-linoleic acid assays. In the first case, IC50 value of the C. vulgare essential oil was determined as 63.0 ± 2.71 μg/ml. IC50 value of thymol and γ-terpinene, the major compounds of the oil, was determined as 161 ± 1.3 μg/ml and 122 ± 2.5 μg/ml, respectively, whereas p-cymene did not show antioxidant activity. In β-carotene-linoleic acid system, C. vulgare essential oil exhibited 52.3 ± 1.19% inhibition against linoleic acid oxidation. In both systems, antioxidant capacities of BHT, curcumine and ascorbic acid were also determined in parallel experiments. © 2006 Elsevier Ltd. All rights reserved. en
heal.journalName Food Chemistry en
dc.identifier.issue 3 en
dc.identifier.volume 103 en
dc.identifier.doi 10.1016/j.foodchem.2006.09.019 en
dc.identifier.spage 766 en
dc.identifier.epage 770 en


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