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Serum ceruloplasmin as a marker in prostate cancer

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dc.contributor.author Fotiou, K en
dc.contributor.author Vaiopoulos, G en
dc.contributor.author Lilakos, K en
dc.contributor.author Giannopoulos, A en
dc.contributor.author Mandalenaki, K en
dc.contributor.author Marinos, G en
dc.contributor.author Koritsiadis, G en
dc.contributor.author Sourdis, J en
dc.contributor.author Konstantinidou, E en
dc.contributor.author Konstantopoulos, K en
dc.date.accessioned 2014-06-06T06:47:27Z
dc.date.available 2014-06-06T06:47:27Z
dc.date.issued 2007 en
dc.identifier.issn 03932249 en
dc.identifier.uri http://62.217.125.90/xmlui/handle/123456789/3598
dc.relation.uri http://www.scopus.com/inward/record.url?eid=2-s2.0-37049028816&partnerID=40&md5=1b8bfc707b11fdfe1fbf08a1e3b25119 en
dc.subject Ceruloplasmin en
dc.subject Prostate specific antigen en
dc.subject Prostatic neoplasms en
dc.subject.other acid phosphatase en
dc.subject.other ceruloplasmin en
dc.subject.other prostate specific antigen en
dc.subject.other acid phosphatase blood level en
dc.subject.other article en
dc.subject.other cancer staging en
dc.subject.other ceruloplasmin blood level en
dc.subject.other clinical article en
dc.subject.other controlled study en
dc.subject.other human en
dc.subject.other male en
dc.subject.other prostate carcinoma en
dc.subject.other prostate hypertrophy en
dc.subject.other sensitivity and specificity en
dc.subject.other Adenocarcinoma en
dc.subject.other Ceruloplasmin en
dc.subject.other Humans en
dc.subject.other Male en
dc.subject.other Predictive Value of Tests en
dc.subject.other Prostate-Specific Antigen en
dc.subject.other Prostatic Hyperplasia en
dc.subject.other Prostatic Neoplasms en
dc.subject.other Sensitivity and Specificity en
dc.subject.other Tumor Markers, Biological en
dc.title Serum ceruloplasmin as a marker in prostate cancer en
heal.type journalArticle en
heal.publicationDate 2007 en
heal.abstract Aim. Serum acid phosphatase and prostate specific antigen have been utilized as disease markers in prostate cancer, one of the commonest cancers of the elderly. Serum ceruloplasmin (Cp) increases in cancer patients; it may be a reliable marker for prostate cancer, but few data are available on specificity and sensitivity of Cp values. Methods. Serum prostate specific antigen (PSA) and Cp was determined in Greek patients suffering from histologically proven prostate carcinoma or benign hyperplasia. The results were compared with those in controls matched for sex and age. Results. In all studied subjects with a prostate cancer, serum Cp values were higher than age-matched healthy controls; they were also higher in cases with benign hyperplasia. No difference in serum Cp was noted among patients with earlier and advanced stages of the tumor. No difference in Cp was also found between benign hyperplasia and normal controls. There exists a significant difference in serum PSA between both prostate cancer and benign hyperplasia cases. There exists also a difference between benign hyperplasia cases and controls. Conclusion. It is suggested that serum Cp may complement the biochemical screening in prostate carcinoma, especially in cases where this cancer is not accompanied by elevation of serum PSA. However, it is not of help in differentiating prostate cancer from prostate benign hyperplasia. en
heal.journalName Minerva Urologica e Nefrologica en
dc.identifier.issue 4 en
dc.identifier.volume 59 en
dc.identifier.spage 407 en
dc.identifier.epage 411 en


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