| dc.contributor.author |
Eiteman, MA |
en |
| dc.date.accessioned |
2014-06-06T06:47:23Z |
|
| dc.date.available |
2014-06-06T06:47:23Z |
|
| dc.date.issued |
2007 |
en |
| dc.identifier.issn |
10567194 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/3565 |
|
| dc.relation.uri |
http://www.scopus.com/inward/record.url?eid=2-s2.0-33846652666&partnerID=40&md5=659b2cb6188c073f384b3b28fea23dbe |
en |
| dc.title |
Genetically engineered E. coli produce lactate |
en |
| heal.type |
journalArticle |
en |
| heal.publicationDate |
2007 |
en |
| heal.abstract |
Mark Eliteman of the Univeristy of Georgia and coworkers have transformed Escherichia coli to obtain strains that produce lactate, which can be easily converted into lactic acid. The lactic fermentation proceeds in an aerobic first phase followed by an anaerobic second phase. The E. coli YYC202 strain contains mutations in the genes encoding the pyruvate dehydrogenase complex, pyruvate formate lyase, pyruvate oxidase and probable phosphoenolpyruvate synthase. The strain also produced succinate as a coproduct. Experiments with carbon-13 labeled compounds in the medium showed that the succinate was derived from acetate in the medium. |
en |
| heal.journalName |
Industrial Bioprocessing |
en |
| dc.identifier.issue |
1 |
en |
| dc.identifier.volume |
29 |
en |
| dc.identifier.spage |
4 |
en |
| dc.identifier.epage |
5 |
en |