| dc.contributor.author |
Theodoropoulos, G |
en |
| dc.contributor.author |
Lazaris, A |
en |
| dc.contributor.author |
Theodoropoulos, V |
en |
| dc.contributor.author |
Papatheodosiou, K |
en |
| dc.contributor.author |
Gazouli, M |
en |
| dc.contributor.author |
Bramis, J |
en |
| dc.contributor.author |
Patsouris, E |
en |
| dc.contributor.author |
Panoussopoulos, D |
en |
| dc.date.accessioned |
2014-06-06T06:46:54Z |
|
| dc.date.available |
2014-06-06T06:46:54Z |
|
| dc.date.issued |
2006 |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1007/s00384-005-0788-4 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/3281 |
|
| dc.subject |
Cell Death |
en |
| dc.subject |
Gene Regulation |
en |
| dc.subject |
Hypoxia Inducible Factor |
en |
| dc.subject |
Lymph Node Metastasis |
en |
| dc.subject |
Multivariate Analysis |
en |
| dc.subject |
Overall Survival |
en |
| dc.subject |
Rectal Cancer |
en |
| dc.subject |
apoptotic index |
en |
| dc.subject |
hypoxia inducible factor 1 |
en |
| dc.subject |
Lymph Node |
en |
| dc.subject |
Vascular Endothelial |
en |
| dc.title |
Hypoxia, angiogenesis and apoptosis markers in locally advanced rectal cancer |
en |
| heal.type |
journalArticle |
en |
| heal.identifier.primary |
10.1007/s00384-005-0788-4 |
en |
| heal.publicationDate |
2006 |
en |
| heal.abstract |
Background and aims Hypoxia-inducible factor 1 (HIF-1) is a critical regulatory protein of cellular response to hypoxia. HIF-1 triggers the angiogenic process through activation of the vascular endothelial factor (VEGF) gene. The bcl-2 anti-apoptotic and the death promoting p53 genes, regulate the apoptotic cell death. We investigated the relationship between hypoxia, angiogenesis and apoptosis and their prognostic impact in patients with |
en |
| heal.journalName |
International Journal of Colorectal Disease |
en |
| dc.identifier.doi |
10.1007/s00384-005-0788-4 |
en |