Cell Wall-Mediated Neuronal Damage in Early Sepsis

dc.contributor.author	Orihuela, C	en
dc.contributor.author	Fillon, S	en
dc.contributor.author	Smith-Sielicki, S	en
dc.contributor.author	Kasmi, K	en
dc.contributor.author	Gao, G	en
dc.contributor.author	Soulis, K	en
dc.contributor.author	Patil, A	en
dc.contributor.author	Murray, P	en
dc.contributor.author	Tuomanen, E	en
dc.date.accessioned	2014-06-06T06:46:53Z
dc.date.available	2014-06-06T06:46:53Z
dc.date.issued	2006	en
dc.identifier.uri	http://dx.doi.org/10.1128/IAI.00022-06	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/3258
dc.subject	Animal Model	en
dc.subject	Central Nervous System	en
dc.subject	Dentate Gyrus	en
dc.subject	Intensive Care Unit	en
dc.subject	Lipopolysaccharide	en
dc.subject	streptococcus pneumoniae	en
dc.subject	Vagus Nerve	en
dc.subject	Blood Brain Barrier	en
dc.subject	Case Fatality Rate	en
dc.subject	Cell Wall	en
dc.subject	Gram Positive	en
dc.title	Cell Wall-Mediated Neuronal Damage in Early Sepsis	en
heal.type	journalArticle	en
heal.identifier.primary	10.1128/IAI.00022-06	en
heal.publicationDate	2006	en
heal.abstract	During sepsis, organ dysfunction occurs independently of invasion of the organ by circulating bacteria. In the case of early encephalopathy, which occurs in up to 70% of septic patients in intensive care units (42), the pathogenesis is un- clear, as it precedes peripheral organ dysfunction and bacterial invasion of the central nervous system (CNS). It is assumed that intravascular inflammation	en
heal.journalName	Infection and Immunity	en
dc.identifier.doi	10.1128/IAI.00022-06	en