| dc.contributor.author |
Constantinou-Kokotou, V |
en |
| dc.contributor.author |
Peristeraki, A |
en |
| dc.contributor.author |
Kokotos, CG |
en |
| dc.contributor.author |
Six, DA |
en |
| dc.contributor.author |
Dennis, EA |
en |
| dc.date.accessioned |
2014-06-06T06:46:39Z |
|
| dc.date.available |
2014-06-06T06:46:39Z |
|
| dc.date.issued |
2005 |
en |
| dc.identifier.issn |
10752617 |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1002/psc.628 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/3123 |
|
| dc.subject |
β-amino acids |
en |
| dc.subject |
2-oxoamides |
en |
| dc.subject |
Inhibitors |
en |
| dc.subject |
Long chain amines |
en |
| dc.subject |
Phospholipase A 2 |
en |
| dc.subject.other |
(1 benzylheptadec 2 enyl)carbamic acid tert butyl ester |
en |
| dc.subject.other |
(1 benzylheptadecyl)carbamic acid tert butyl ester |
en |
| dc.subject.other |
(1 benzyltridec 2 enyl)carbamic acid tert butyl ester |
en |
| dc.subject.other |
(1 benzyltridecyl)carbamic acid tert butyl ester |
en |
| dc.subject.other |
1 benzylheptadecylammonium chloride |
en |
| dc.subject.other |
1 benzyltridecylammonium chloride |
en |
| dc.subject.other |
2 hydroxydodecanoic acid(1 benzyltridecyl)amide |
en |
| dc.subject.other |
2 oxoamide derivative |
en |
| dc.subject.other |
2 oxooctanoic acid(1 benzylheptadecyl)amide |
en |
| dc.subject.other |
3 (2 oxododecanoylamino)pentadecanoic acid |
en |
| dc.subject.other |
3 (2 oxooctanoylamino)nonadecanoic acid |
en |
| dc.subject.other |
antiinflammatory agent |
en |
| dc.subject.other |
beta amino acid |
en |
| dc.subject.other |
carboxyl group |
en |
| dc.subject.other |
phenyl group |
en |
| dc.subject.other |
phospholipase A2 inhibitor |
en |
| dc.subject.other |
unclassified drug |
en |
| dc.subject.other |
aerobic metabolism |
en |
| dc.subject.other |
article |
en |
| dc.subject.other |
catalysis |
en |
| dc.subject.other |
controlled study |
en |
| dc.subject.other |
deprotection reaction |
en |
| dc.subject.other |
drug activity |
en |
| dc.subject.other |
drug synthesis |
en |
| dc.subject.other |
enzyme assay |
en |
| dc.subject.other |
enzyme inhibition |
en |
| dc.subject.other |
enzyme specificity |
en |
| dc.subject.other |
hydrogenation |
en |
| dc.subject.other |
nuclear magnetic resonance spectroscopy |
en |
| dc.subject.other |
olefination |
en |
| dc.subject.other |
priority journal |
en |
| dc.subject.other |
proton nuclear magnetic resonance |
en |
| dc.subject.other |
Amino Acids |
en |
| dc.subject.other |
Formic Acid Esters |
en |
| dc.subject.other |
Phenylalanine |
en |
| dc.subject.other |
Phospholipases A |
en |
| dc.subject.other |
Pyridines |
en |
| dc.title |
Synthesis and activity of 2-oxoamides containing long chain β-amino acids |
en |
| heal.type |
journalArticle |
en |
| heal.identifier.primary |
10.1002/psc.628 |
en |
| heal.publicationDate |
2005 |
en |
| heal.abstract |
2-Oxoamides based on long chain β-amino acids were synthesized. 1-Benzyl substituted long chain amines, needed for such synthesis, were synthesized starting from Boc-phenylalaninol. The oxidative conversion of a phenyl group to a carboxyl group was used as the key transformation synthetic step. The compounds synthesized were studied for their activity against GIVA PLA 2, and were proven to be weak inhibitors. Copyright © 2004 European Peptide Society and John Wiley & Sons, Ltd. |
en |
| heal.journalName |
Journal of Peptide Science |
en |
| dc.identifier.issue |
7 |
en |
| dc.identifier.volume |
11 |
en |
| dc.identifier.doi |
10.1002/psc.628 |
en |
| dc.identifier.spage |
431 |
en |
| dc.identifier.epage |
435 |
en |