| dc.contributor.author |
Couladouros, EA |
en |
| dc.contributor.author |
Mihou, AP |
en |
| dc.contributor.author |
Bouzas, EA |
en |
| dc.date.accessioned |
2014-06-06T06:46:12Z |
|
| dc.date.available |
2014-06-06T06:46:12Z |
|
| dc.date.issued |
2004 |
en |
| dc.identifier.issn |
1523-7060 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/2840 |
|
| dc.subject.classification |
Chemistry, Organic |
en |
| dc.subject.other |
RUTHENIUM CARBENE COMPLEXES |
en |
| dc.subject.other |
OLEFIN METATHESIS |
en |
| dc.subject.other |
SALICYLIHALAMIDE-A |
en |
| dc.subject.other |
IMIDAZOL-2-YLIDENE LIGANDS |
en |
| dc.subject.other |
CARBONYL-COMPOUNDS |
en |
| dc.subject.other |
NATURAL-PRODUCTS |
en |
| dc.subject.other |
MACROLIDE |
en |
| dc.subject.other |
CHEMISTRY |
en |
| dc.subject.other |
LASIODIPLODIN |
en |
| dc.subject.other |
INHIBITORS |
en |
| dc.title |
First total synthesis of trans- and cis-resorcylide: Remarkable hydrogen-bond-controlled, stereospecific ring-closing metathesis |
en |
| heal.type |
journalArticle |
en |
| heal.language |
English |
en |
| heal.publicationDate |
2004 |
en |
| heal.abstract |
[GRAPHICS] Stereospecific synthesis of the pair of natural macrolides, trans- and cis-resorcylide, was performed using ring-closing metathesis on dienes 3 and 4, which lack or feature an intramolecular H-bond, respectively. An effective Stille carbonylative coupling of benzyl chlorides 11 and 15 was employed for their preparation. The influence of intramolecular H-bonding on the interconversions of resorcylides was also studied. |
en |
| heal.publisher |
AMER CHEMICAL SOC |
en |
| heal.journalName |
ORGANIC LETTERS |
en |
| dc.identifier.issue |
6 |
en |
| dc.identifier.volume |
6 |
en |
| dc.identifier.isi |
ISI:000220207300030 |
en |
| dc.identifier.spage |
977 |
en |
| dc.identifier.epage |
980 |
en |