| dc.contributor.author |
Tzamalis, P |
en |
| dc.contributor.author |
Bethanis, K |
en |
| dc.contributor.author |
Hountas, A |
en |
| dc.contributor.author |
Tsoucaris, G |
en |
| dc.date.accessioned |
2014-06-06T06:45:37Z |
|
| dc.date.available |
2014-06-06T06:45:37Z |
|
| dc.date.issued |
2003 |
en |
| dc.identifier.issn |
01087673 |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1107/S0108767302018810 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/2545 |
|
| dc.subject.other |
calponin |
en |
| dc.subject.other |
ribonuclease |
en |
| dc.subject.other |
algorithm |
en |
| dc.subject.other |
article |
en |
| dc.subject.other |
Aspergillus |
en |
| dc.subject.other |
crystal |
en |
| dc.subject.other |
crystallography |
en |
| dc.subject.other |
human |
en |
| dc.subject.other |
mathematical analysis |
en |
| dc.subject.other |
nonhuman |
en |
| dc.subject.other |
protein structure |
en |
| dc.subject.other |
structure analysis |
en |
| dc.subject.other |
Thermotoga maritima |
en |
| dc.subject.other |
Alcohol Oxidoreductases |
en |
| dc.subject.other |
Crystallography, X-Ray |
en |
| dc.subject.other |
Models, Chemical |
en |
| dc.subject.other |
Proteins |
en |
| dc.subject.other |
Ribonuclease T1 |
en |
| dc.subject.other |
Aspergillus |
en |
| dc.subject.other |
Thermotoga |
en |
| dc.subject.other |
Thermotoga maritima |
en |
| dc.title |
The crystallographic symmetry test for the correctness of a set of phases |
en |
| heal.type |
journalArticle |
en |
| heal.identifier.primary |
10.1107/S0108767302018810 |
en |
| heal.publicationDate |
2003 |
en |
| heal.abstract |
One of the most important problems in the application of direct methods for large structures is to establish reliable consistency criteria for the correctness of a phasing trial. The introduction in the twin variables method [Bethanis, Tzamalis, Hountas, Mishnev & Tsoucaris (2000). Acta Cryst. A56, 105-111] of a new criterion based on the crystallographic symmetry consists of testing the phase extension and refinement algorithm by deliberately sacrificing the spacegroup-symmetry information in the auxiliary variable set then using its gradual re-appearance as a criterion for correctness. In the present paper, the crystallographic symmetry test has been used in the implementation of the twin algorithm in two different ways: (i) as an overall test throughout the iterations that is likely to reflect the correctness of the phasing procedure for each one of the extension trials in a macromolecular phasing environment; (ii) as a convenient criterion to determine the optimum cycle for freeing the initial phases used by the algorithm for the phase-extension procedure. |
en |
| heal.journalName |
Acta Crystallographica Section A: Foundations of Crystallography |
en |
| dc.identifier.issue |
1 |
en |
| dc.identifier.volume |
59 |
en |
| dc.identifier.doi |
10.1107/S0108767302018810 |
en |
| dc.identifier.spage |
28 |
en |
| dc.identifier.epage |
33 |
en |