| dc.contributor.author |
Constantinou-Kokotou, V |
en |
| dc.contributor.author |
Magrioti, V |
en |
| dc.date.accessioned |
2014-06-06T06:45:37Z |
|
| dc.date.available |
2014-06-06T06:45:37Z |
|
| dc.date.issued |
2003 |
en |
| dc.identifier.issn |
09394451 |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1007/s00726-002-0403-8 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/2542 |
|
| dc.subject |
Amino aldehydes |
en |
| dc.subject |
Chiral synthons |
en |
| dc.subject |
N,N-di-Boc-Glutamate semialdehydes |
en |
| dc.subject |
Unnatural amino acids |
en |
| dc.subject |
Wittig reaction |
en |
| dc.subject.other |
aldehyde derivative |
en |
| dc.subject.other |
aspartic acid derivative |
en |
| dc.subject.other |
glutamic acid derivative |
en |
| dc.subject.other |
n,n di butoxycarbonylaspartate |
en |
| dc.subject.other |
n,n di butoxycarbonylglutamate |
en |
| dc.subject.other |
unclassified drug |
en |
| dc.subject.other |
amino acid synthesis |
en |
| dc.subject.other |
chemical reaction |
en |
| dc.subject.other |
chirality |
en |
| dc.subject.other |
methodology |
en |
| dc.subject.other |
optical rotation |
en |
| dc.subject.other |
priority journal |
en |
| dc.subject.other |
reaction analysis |
en |
| dc.subject.other |
review |
en |
| dc.subject.other |
Wittig reaction |
en |
| dc.subject.other |
Aldehydes |
en |
| dc.subject.other |
Amino Acids |
en |
| dc.subject.other |
Aspartic Acid |
en |
| dc.subject.other |
Glutamates |
en |
| dc.subject.other |
Models, Chemical |
en |
| dc.subject.other |
Molecular Structure |
en |
| dc.subject.other |
Stereoisomerism |
en |
| dc.title |
Synthesis and use of N,N-di-Boc-glutamate γ-semialdehydes and related aldehydes |
en |
| heal.type |
other |
en |
| heal.identifier.primary |
10.1007/s00726-002-0403-8 |
en |
| heal.publicationDate |
2003 |
en |
| heal.abstract |
This review article focuses on the synthesis and reactions of N,N-di-Boc glutamate and aspartate semialdehydes as well as related aldehydes. These building blocks are prepared according to various strategies from glutamic and aspartic acids and find interesting synthetic applications. In the first part, the methods for the synthesis of N,N-di-Boc-amino aldehydes are summarized. The applications of these chiral synthons for the synthesis of unnatural amino acids and other bioactive compounds are discussed in the second section. |
en |
| heal.journalName |
Amino Acids |
en |
| dc.identifier.issue |
3 |
en |
| dc.identifier.volume |
24 |
en |
| dc.identifier.doi |
10.1007/s00726-002-0403-8 |
en |
| dc.identifier.spage |
231 |
en |
| dc.identifier.epage |
243 |
en |