Selective uptake of fatty acids by the yeast Yarrowia lipolytica

dc.contributor.author	Papanikolaou, S	en
dc.contributor.author	Aggelis, G	en
dc.date.accessioned	2014-06-06T06:45:36Z
dc.date.available	2014-06-06T06:45:36Z
dc.date.issued	2003	en
dc.identifier.issn	14387697	en
dc.identifier.uri	http://dx.doi.org/10.1002/ejlt.200300858	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/2533
dc.subject	Fatty acid specificity	en
dc.subject	Lipid biomodification	en
dc.subject	Yarrowia lipolytica	en
dc.subject.other	fat	en
dc.subject.other	fatty acid	en
dc.subject.other	article	en
dc.subject.other	cell transport	en
dc.subject.other	concentration (parameters)	en
dc.subject.other	controlled study	en
dc.subject.other	fatty acid transport	en
dc.subject.other	fungus culture	en
dc.subject.other	lipid analysis	en
dc.subject.other	lipid composition	en
dc.subject.other	lipid storage	en
dc.subject.other	nonhuman	en
dc.subject.other	quantitative analysis	en
dc.subject.other	Yarrowia lipolytica	en
dc.subject.other	yeast	en
dc.subject.other	Fungi	en
dc.subject.other	Yarrowia lipolytica	en
dc.title	Selective uptake of fatty acids by the yeast Yarrowia lipolytica	en
heal.type	journalArticle	en
heal.identifier.primary	10.1002/ejlt.200300858	en
heal.publicationDate	2003	en
heal.abstract	Yarrowia lipolytica, when cultivated on mixtures of free fatty acid substrates was found to remove C12:0, C14:0, Δ9C18:1, Δ9,12C18:2 and Δ9,12,15C18:3 at significantly higher rates than C16:0 and C18:0, regardless of fatty acid composition of the initial substrate. C12:0, C14:0 and Δ9,12,15C18:3 were specifically and completely removed from the substrate, while Δ9C18:1 and Δ9,12C18:2 concentrations decreased by 55-80 wt-% in comparison with initial concentrations. In contrast, concentration of C18:0 increased 2.1-3.5 fold in the substrate. Although C18:0 was removed slowly from the substrate, this fatty acid was selectively accumulated in the storage lipid. Inversely, only low quantities of Δ9C18:1 and Δ9,12C18:2 and traces of C12:0, C14:0 and Δ9,12,15C18:3 were accumulated in the storage lipid. During storage lipid breakdown, cellular C16:0 and Δ9C18:1 were taken up more rapidly than C18:0. We concluded that the capability of Yarrowia lipolytica to selectively remove several fatty acids from the substrate and accumulate others could be used in modification of the composition of selected mixtures of fatty acids and probably of common fats, to produce ""new"" fats with a predetermined composition.	en
heal.journalName	European Journal of Lipid Science and Technology	en
dc.identifier.issue	11	en
dc.identifier.volume	105	en
dc.identifier.doi	10.1002/ejlt.200300858	en
dc.identifier.spage	651	en
dc.identifier.epage	655	en