| dc.contributor.author |
Candan, F |
en |
| dc.contributor.author |
Unlu, M |
en |
| dc.contributor.author |
Tepe, B |
en |
| dc.contributor.author |
Daferera, D |
en |
| dc.contributor.author |
Polissiou, M |
en |
| dc.contributor.author |
Sokmen, A |
en |
| dc.contributor.author |
Akpulat, HA |
en |
| dc.date.accessioned |
2014-06-06T06:45:26Z |
|
| dc.date.available |
2014-06-06T06:45:26Z |
|
| dc.date.issued |
2003 |
en |
| dc.identifier.issn |
03788741 |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1016/S0378-8741(03)00149-1 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/2441 |
|
| dc.subject |
Achillea millefolium |
en |
| dc.subject |
Antimicrobial activity |
en |
| dc.subject |
Antioxidant activity |
en |
| dc.subject |
Essential oil |
en |
| dc.subject |
GC-MS |
en |
| dc.subject |
Methanol extracts |
en |
| dc.subject.other |
1,1 diphenyl 2 picrylhydrazyl |
en |
| dc.subject.other |
Achillea millefolium extract |
en |
| dc.subject.other |
beta pinene |
en |
| dc.subject.other |
borneol |
en |
| dc.subject.other |
camphor |
en |
| dc.subject.other |
chemical compound |
en |
| dc.subject.other |
deoxyribose |
en |
| dc.subject.other |
edetic acid |
en |
| dc.subject.other |
essential oil |
en |
| dc.subject.other |
hydrogen peroxide |
en |
| dc.subject.other |
hydroxyl radical |
en |
| dc.subject.other |
iron |
en |
| dc.subject.other |
methanol |
en |
| dc.subject.other |
radical |
en |
| dc.subject.other |
terpineol |
en |
| dc.subject.other |
water |
en |
| dc.subject.other |
Acinetobacter lwoffii |
en |
| dc.subject.other |
antimicrobial activity |
en |
| dc.subject.other |
antioxidant activity |
en |
| dc.subject.other |
article |
en |
| dc.subject.other |
Candida albicans |
en |
| dc.subject.other |
Candida krusei |
en |
| dc.subject.other |
chemical composition |
en |
| dc.subject.other |
Clostridium perfringens |
en |
| dc.subject.other |
drug activity |
en |
| dc.subject.other |
drug mechanism |
en |
| dc.subject.other |
enzyme inhibition |
en |
| dc.subject.other |
Eucalyptus |
en |
| dc.subject.other |
gas chromatography |
en |
| dc.subject.other |
IC 50 |
en |
| dc.subject.other |
in vitro study |
en |
| dc.subject.other |
lipid peroxidation |
en |
| dc.subject.other |
liver homogenate |
en |
| dc.subject.other |
mass spectrometry |
en |
| dc.subject.other |
Mycobacterium smegmatis |
en |
| dc.subject.other |
nonhuman |
en |
| dc.subject.other |
polarization |
en |
| dc.subject.other |
rat |
en |
| dc.subject.other |
solubility |
en |
| dc.subject.other |
Streptococcus pneumonia |
en |
| dc.subject.other |
Achillea |
en |
| dc.subject.other |
Anti-Bacterial Agents |
en |
| dc.subject.other |
Antioxidants |
en |
| dc.subject.other |
Bacteria |
en |
| dc.subject.other |
Candida |
en |
| dc.subject.other |
Gas Chromatography-Mass Spectrometry |
en |
| dc.subject.other |
Methanol |
en |
| dc.subject.other |
Oils, Volatile |
en |
| dc.subject.other |
Phytotherapy |
en |
| dc.subject.other |
Plant Extracts |
en |
| dc.subject.other |
Plant Oils |
en |
| dc.title |
Antioxidant and antimicrobial activity of the essential oil and methanol extracts of Achillea millefolium subsp. millefolium Afan. (Asteraceae) |
en |
| heal.type |
journalArticle |
en |
| heal.identifier.primary |
10.1016/S0378-8741(03)00149-1 |
en |
| heal.publicationDate |
2003 |
en |
| heal.abstract |
The in vitro antimicrobial and antioxidant activities of the essential oil and methanol extracts of Achillea millefolium subsp. millefolium Afan. (Asteraceae) were investigated. GC-MS analysis of the essential oil resulted in the identification of 36 compounds constituting 90.8% of the total oil. Eucalyptol, camphor, α-terpineol, β-pinene, and borneol were the principal components comprising 60.7% of the oil. The oil strongly reduced the diphenylpicrylhydrazyl radical (IC 50=1.56μg/ml) and exhibited hydroxyl radical scavenging effect in the Fe 3+-EDTA-H 2O 2 deoxyribose system (IC 50=2.7μg/ml). It also inhibited the nonenzymatic lipid peroxidation of rat liver homogenate (IC 50=13.5μg/ml). The polar phase of the extract showed antioxidant activity. The oil showed antimicrobial activity against Streptococcus pneumoniae, Clostridium perfringens, Candida albicans, Mycobacterium smegmatis, Acinetobacter lwoffii and Candida krusei while water-insoluble parts of the methanolic extracts exhibited slight or no activity. This study confirms that the essential oil of Achillea millefolium possesses antioxidant and antimicrobial properties in vitro. © 2003 Elsevier Science Ireland Ltd. All rights reserved. |
en |
| heal.journalName |
Journal of Ethnopharmacology |
en |
| dc.identifier.issue |
2-3 |
en |
| dc.identifier.volume |
87 |
en |
| dc.identifier.doi |
10.1016/S0378-8741(03)00149-1 |
en |
| dc.identifier.spage |
215 |
en |
| dc.identifier.epage |
220 |
en |