| dc.contributor.author |
Zoumpoulakis, P |
en |
| dc.contributor.author |
Daliani, I |
en |
| dc.contributor.author |
Zervou, M |
en |
| dc.contributor.author |
Kyrikou, I |
en |
| dc.contributor.author |
Siapi, E |
en |
| dc.contributor.author |
Lamprinidis, G |
en |
| dc.contributor.author |
Mikros, E |
en |
| dc.contributor.author |
Mavromoustakos, T |
en |
| dc.date.accessioned |
2014-06-06T06:45:20Z |
|
| dc.date.available |
2014-06-06T06:45:20Z |
|
| dc.date.issued |
2003 |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1016/S0009-3084(03)00053-7 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/2384 |
|
| dc.subject |
Differential Scanning Calorimetry |
en |
| dc.subject |
Dynamic Change |
en |
| dc.subject |
Lipid Bilayer |
en |
| dc.subject |
Molecular Modeling |
en |
| dc.subject |
Phase Transition |
en |
| dc.title |
Losartan’s molecular basis of interaction with membranes and AT 1 receptor |
en |
| heal.type |
journalArticle |
en |
| heal.identifier.primary |
10.1016/S0009-3084(03)00053-7 |
en |
| heal.publicationDate |
2003 |
en |
| heal.abstract |
Physicochemical methods were used to study the thermal and dynamic changes caused by losartan in the membrane bilayers. In addition, molecular modeling was implemented to explore its topography both in membranes and AT1 receptor. Its incorporation resulted in the modification of thermal profile of dipalmitoyl phosphatidylcholine (DPPC) bilayers in a concentration dependent way up to 20mol% as it is depicted |
en |
| heal.journalName |
Chemistry and Physics of Lipids |
en |
| dc.identifier.doi |
10.1016/S0009-3084(03)00053-7 |
en |