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Synthesis and antioxidant activity of 3-substituted guaiazulene derivatives

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dc.contributor.author Pratsinis, H en
dc.contributor.author Haroutounian, S en
dc.date.accessioned 2014-06-06T06:45:09Z
dc.date.available 2014-06-06T06:45:09Z
dc.date.issued 2002 en
dc.identifier.issn 10575634 en
dc.identifier.uri http://dx.doi.org/10.1080/10575630290013585 en
dc.identifier.uri http://62.217.125.90/xmlui/handle/123456789/2272
dc.subject Antioxidant activity en
dc.subject Cell proliferation en
dc.subject Guaiazulene en
dc.subject.other 1,1 diphenyl 2 picrylhydrazyl en
dc.subject.other 3 guaiazulene derivative en
dc.subject.other 3 vinylguaiazulene en
dc.subject.other alpha tocopherol en
dc.subject.other antimitotic agent en
dc.subject.other antioxidant en
dc.subject.other guaiazulene en
dc.subject.other scavenger en
dc.subject.other unclassified drug en
dc.subject.other antioxidant activity en
dc.subject.other article en
dc.subject.other cell level en
dc.subject.other cell proliferation en
dc.subject.other chemical reaction en
dc.subject.other controlled study en
dc.subject.other drug potency en
dc.subject.other drug screening en
dc.subject.other drug structure en
dc.subject.other drug synthesis en
dc.subject.other human en
dc.subject.other human cell en
dc.subject.other inhibition kinetics en
dc.subject.other leukemia cell en
dc.subject.other monitoring en
dc.subject.other promyelocytic leukemia en
dc.subject.other scavenging system en
dc.subject.other structure analysis en
dc.subject.other alpha-Tocopherol en
dc.subject.other Antineoplastic Agents en
dc.subject.other Antioxidants en
dc.subject.other Azulenes en
dc.subject.other Catalysis en
dc.subject.other Drug Screening Assays, Antitumor en
dc.subject.other Free Radical Scavengers en
dc.subject.other Humans en
dc.subject.other Leukemia, Promyelocytic, Acute en
dc.subject.other Lipid Peroxidation en
dc.subject.other Molecular Structure en
dc.subject.other Sesquiterpenes en
dc.subject.other Thymidine en
dc.subject.other Time Factors en
dc.title Synthesis and antioxidant activity of 3-substituted guaiazulene derivatives en
heal.type journalArticle en
heal.identifier.primary 10.1080/10575630290013585 en
heal.publicationDate 2002 en
heal.abstract A series of 3-substituted guaiazulene derivatives has been synthesized and their antioxidant properties were evaluated by monitoring their capacity for scavenging the stable free-radical DPPH. 3-Vinylguaiazulene was the most potent, possessing antioxidant activity superior than α-tocopherol. These derivatives were also moderate inhibitors of the proliferation of human promyelocytic leukemia cells. en
heal.journalName Natural Product Letters en
dc.identifier.issue 3 en
dc.identifier.volume 16 en
dc.identifier.doi 10.1080/10575630290013585 en
dc.identifier.spage 201 en
dc.identifier.epage 205 en


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