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Analysis of aggregate exposure to chlorpyrifos in the NHEXAS-Maryland investigation

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dc.contributor.author Pang, Y en
dc.contributor.author MacIntosh, DL en
dc.contributor.author Camann, DE en
dc.contributor.author Ryan, PB en
dc.date.accessioned 2014-06-06T06:44:47Z
dc.date.available 2014-06-06T06:44:47Z
dc.date.issued 2002 en
dc.identifier.issn 00916765 en
dc.identifier.uri http://62.217.125.90/xmlui/handle/123456789/2067
dc.relation.uri http://www.scopus.com/inward/record.url?eid=2-s2.0-0036196491&partnerID=40&md5=36e3369917c594e02bfa7e558652e060 en
dc.subject Aggregate exposure en
dc.subject Chlorpyrifos en
dc.subject Dust en
dc.subject Indoor air en
dc.subject Reliability en
dc.subject Soil en
dc.subject Solid food en
dc.subject.other chlorpyrifos en
dc.subject.other pesticide en
dc.subject.other accuracy en
dc.subject.other adolescent en
dc.subject.other adult en
dc.subject.other aged en
dc.subject.other ambient air en
dc.subject.other article en
dc.subject.other chemical analysis en
dc.subject.other concentration (parameters) en
dc.subject.other controlled study en
dc.subject.other correlation function en
dc.subject.other environmental exposure en
dc.subject.other food analysis en
dc.subject.other health survey en
dc.subject.other human en
dc.subject.other indoor air pollution en
dc.subject.other inhalation en
dc.subject.other major clinical study en
dc.subject.other priority journal en
dc.subject.other randomization en
dc.subject.other reliability en
dc.subject.other risk assessment en
dc.subject.other sampling en
dc.subject.other school child en
dc.subject.other self report en
dc.subject.other soil analysis en
dc.subject.other United States en
dc.subject.other Activities of Daily Living en
dc.subject.other Air Pollution, Indoor en
dc.subject.other Chlorpyrifos en
dc.subject.other Dust en
dc.subject.other Environmental Exposure en
dc.subject.other Environmental Monitoring en
dc.subject.other Floors and Floorcoverings en
dc.subject.other Humans en
dc.subject.other Insecticides en
dc.subject.other Maryland en
dc.subject.other Sensitivity and Specificity en
dc.title Analysis of aggregate exposure to chlorpyrifos in the NHEXAS-Maryland investigation en
heal.type journalArticle en
heal.publicationDate 2002 en
heal.abstract As part of the National Human Exposure Assessment Survey (NHEXAS) in Maryland, we collected indoor air, carpet dust, exterior soil, and duplicate diet samples from a stratified random sample of 80 individuals to evaluate aggregate daily exposure, contributions of specific pathways of exposure, and temporal variation in exposure to chlorpyrifos. We collected samples from each participant in up to six equally spaced sampling cycles over a year and analyzed them for chlorpyrifos. We used chlorpyrifos concentrations in each medium and self-reported rates of time spent inside at home, time and frequency of contact with carpet, frequency of contact with soil, and weights of the duplicate diet samples to derive exposure to chlorpyrifos from each medium as well as average daily aggregate exposure (nanograms per day). The mean aggregate daily exposure to chlorpyrifos of 36 measurements obtained from 31 people was 1,390 ng/day (SD, 2,770 ng/day). Exposure from inhalation of indoor air accounted for 84.7% of aggregate daily exposure to chlorpyrifos on average. Chlorpyrifos concentrations in indoor air and carpet dust and the corresponding exposure rates were significantly correlated. Repeated short-term measurements of chlorpyrifos in carpet dust from individual residences were strongly correlated over time (reliability coefficient, R = 0.90), whereas the short-term measurements of chlorpyrifos in indoor air (R = 0.55) and solid food (R = 0.03) had moderate to weak reliability. Exposure to chlorpyrifos through those media and in aggregate based on direct measurements reported in this study can be used to understand better the accuracy of pesticide safety assessments. en
heal.journalName Environmental Health Perspectives en
dc.identifier.issue 3 en
dc.identifier.volume 110 en
dc.identifier.spage 235 en
dc.identifier.epage 240 en


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