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Bioelectric recognition assay (BERA)

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dc.contributor.author Kintzios, S en
dc.contributor.author Pistola, E en
dc.contributor.author Panagiotopoulos, P en
dc.contributor.author Bomsel, M en
dc.contributor.author Alexandropoulos, N en
dc.contributor.author Bem, F en
dc.contributor.author Ekonomou, G en
dc.contributor.author Biselis, J en
dc.contributor.author Levin, R en
dc.date.accessioned 2014-06-06T06:44:35Z
dc.date.available 2014-06-06T06:44:35Z
dc.date.issued 2001 en
dc.identifier.issn 09565663 en
dc.identifier.uri http://dx.doi.org/10.1016/S0956-5663(01)00127-0 en
dc.identifier.uri http://62.217.125.90/xmlui/handle/123456789/1964
dc.subject Biosensor en
dc.subject Cell immobilization en
dc.subject Electrophysiological response en
dc.subject Herbicide en
dc.subject Viruses en
dc.subject.other Hepatitis C en
dc.subject.other Cells en
dc.subject.other Cost effectiveness en
dc.subject.other Gels en
dc.subject.other Herbicides en
dc.subject.other Physiology en
dc.subject.other Viruses en
dc.subject.other Biosensors en
dc.subject.other glyphosate en
dc.subject.other herbicide en
dc.subject.other aqueous solution en
dc.subject.other article en
dc.subject.other biosensor en
dc.subject.other electrode en
dc.subject.other electrophysiology en
dc.subject.other Hepatitis C virus en
dc.subject.other nonhuman en
dc.subject.other plant virus en
dc.subject.other technique en
dc.subject.other virus detection en
dc.subject.other Animals en
dc.subject.other Biosensing Techniques en
dc.subject.other Cell Survival en
dc.subject.other Cells, Immobilized en
dc.subject.other Humans en
dc.subject.other Hepatitis C virus en
dc.title Bioelectric recognition assay (BERA) en
heal.type journalArticle en
heal.identifier.primary 10.1016/S0956-5663(01)00127-0 en
heal.publicationDate 2001 en
heal.abstract A novel biosensory method has been developed for the determination of various chemical and biological molecules by assessing their electrophysiological interactions with a group of cells and cell components immobilized in a gel matrix that preserves their 'physiological' functions. The method was applied for the detection of: (i) hepatitis C virus in human blood samples; (ii) plant viruses; and (iii) a herbicide (glyphosate) in aqueous solutions. It was able to rapidly (assay time 3-5 min) and specifically detect the molecules in question at a concentration lower than 100 pg/ml, among other compounds f similar structure. The potential use of BERA biosensors for a rapid and cost-efficient molecule determination without prior knowledge of a specific receptor-molecule interaction is discussed. © 2001 Elsevier Science B.V. en
heal.journalName Biosensors and Bioelectronics en
dc.identifier.issue 4-5 en
dc.identifier.volume 16 en
dc.identifier.doi 10.1016/S0956-5663(01)00127-0 en
dc.identifier.spage 325 en
dc.identifier.epage 336 en


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