Analysis of dietary intake of selected metals in the NHEXAS-Maryland investigation

dc.contributor.author	Ryan, PB	en
dc.contributor.author	Scanlon, KA	en
dc.contributor.author	MacIntosh, DL	en
dc.date.accessioned	2014-06-06T06:44:25Z
dc.date.available	2014-06-06T06:44:25Z
dc.date.issued	2001	en
dc.identifier.issn	00916765	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/1863
dc.relation.uri	http://www.scopus.com/inward/record.url?eid=2-s2.0-0035057519&partnerID=40&md5=227e8c362e270f4ff4106bf8215c4066	en
dc.subject	Arsenic	en
dc.subject	Cadmium	en
dc.subject	Chromium	en
dc.subject	Chronic exposure	en
dc.subject	Dietary exposure	en
dc.subject	Lead	en
dc.subject	NHEXAS-Maryland	en
dc.subject.other	arsenic	en
dc.subject.other	cadmium	en
dc.subject.other	chromium	en
dc.subject.other	lead	en
dc.subject.other	metal	en
dc.subject.other	algorithm	en
dc.subject.other	article	en
dc.subject.other	audiovisual equipment	en
dc.subject.other	concentration (parameters)	en
dc.subject.other	controlled study	en
dc.subject.other	dietary intake	en
dc.subject.other	environmental exposure	en
dc.subject.other	epidemiology	en
dc.subject.other	food contamination	en
dc.subject.other	food intake	en
dc.subject.other	information processing	en
dc.subject.other	observation	en
dc.subject.other	pilot study	en
dc.subject.other	prediction	en
dc.subject.other	priority journal	en
dc.subject.other	regression analysis	en
dc.subject.other	risk assessment	en
dc.subject.other	Arsenic	en
dc.subject.other	Cadmium	en
dc.subject.other	Chromium	en
dc.subject.other	Diet	en
dc.subject.other	Environmental Exposure	en
dc.subject.other	Food Analysis	en
dc.subject.other	Humans	en
dc.subject.other	Lead	en
dc.subject.other	Maryland	en
dc.subject.other	Metals	en
dc.subject.other	Multivariate Analysis	en
dc.subject.other	Pilot Projects	en
dc.subject.other	Sensitivity and Specificity	en
dc.title	Analysis of dietary intake of selected metals in the NHEXAS-Maryland investigation	en
heal.type	journalArticle	en
heal.publicationDate	2001	en
heal.abstract	As part of a large pilot investigation of multimedia exposure to several classes of environmental contaminants, the National Human Exposure Assessment Survey (NHEXAS)-Maryland study, we collected 388 semiquantitative food checklists and duplicate diet solid food samples, analyzed for arsenic, cadmium, chromium, and lead concentrations, from 80 individuals in Maryland in 1995-1996 in a repeated measures design. Here we explore several methods to infer foods most strongly associated with concentrations of these metals observed in the duplicate diet in our data set. We employed two techniques in which logarithmically transformed metal concentrations in the duplicate diet were regressed on individual food item consumption using algorithms designed to identify the foods most associated with the observed duplicate diet concentrations. We also employed an alternative strategy in which foods to be used as independent variables in regression were selected using data collected in national food consumption and residue surveys, with regression procedures proceeding with the selected foods in a similar manner. The concordance of foods selected as major predictors among these three techniques is noteworthy and is discussed. Finally, the Dietary Exposure Potential Model (DEPM) was used with the Dietary Checklist data to predict duplicate diet concentrations within our sample. A comparison between the predicted values and those observed gave R2 values of 0.180, 0.206, and 0.076 for As, Cd, and Pb, respectively (p <0.0001 in all cases). We discuss the significance of these observations and the implications for dietary-exposure-based risk analysis and dietary intake epidemiology.	en
heal.journalName	Environmental Health Perspectives	en
dc.identifier.issue	2	en
dc.identifier.volume	109	en
dc.identifier.spage	121	en
dc.identifier.epage	128	en