| dc.contributor.author |
Kimbaris, A |
en |
| dc.contributor.author |
Varvounis, G |
en |
| dc.date.accessioned |
2014-06-06T06:44:11Z |
|
| dc.date.available |
2014-06-06T06:44:11Z |
|
| dc.date.issued |
2000 |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1016/S0040-4020(00)00922-4 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/1726 |
|
| dc.subject |
Sodium Hydroxide |
en |
| dc.subject |
Zinc |
en |
| dc.title |
Reduction of 2- and 3-Acylpyrroles. A New Synthesis of the Pyrrolo[1,2- b]cinnolin-10-one Ring System from 1-(4-Methylphenyl)sulfonyl-1 H-pyrrole |
en |
| heal.type |
journalArticle |
en |
| heal.identifier.primary |
10.1016/S0040-4020(00)00922-4 |
en |
| heal.publicationDate |
2000 |
en |
| heal.abstract |
Reduction of (2-nitrophenyl)(1H-pyrrol-2-yl)methanone 4 with zinc and ammonium chloride gave 5,10-dihydro-pyrrolo[1,2-b]cinnolin-10-one 5 and (2-hydroxylaminophenyl)(1H-pyrrol-2-yl)methanone 6 whereas reduction of 4 with zinc and sodium hydroxide gave only 5. Reaction of (2-nitrophenyl)(1H-pyrrol-3-yl)methanone 10 with zinc and ammonium chloride or zinc and sodium hydroxide afforded (2-nitrosophenyl)(1H-pyrrol-3-yl)methanone 11 and 2-aminophenyl)(1H-pyrrol-3-yl)methanone 12 or 12 as a single product, respectively. Sodium borohydride reduction of (2-nitrophenyl)(1-methyl-1H-pyrrol-2-yl)methanone 13 |
en |
| heal.journalName |
Tetrahedron |
en |
| dc.identifier.doi |
10.1016/S0040-4020(00)00922-4 |
en |