| dc.contributor.author |
Kokotos, G |
en |
| dc.contributor.author |
Constantinou-Kokotou, V |
en |
| dc.contributor.author |
Noula, C |
en |
| dc.contributor.author |
Hadjipavlou-Litina, D |
en |
| dc.date.accessioned |
2014-06-06T06:43:59Z |
|
| dc.date.available |
2014-06-06T06:43:59Z |
|
| dc.date.issued |
1999 |
en |
| dc.identifier.issn |
00244201 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/1607 |
|
| dc.relation.uri |
http://www.scopus.com/inward/record.url?eid=2-s2.0-0032923791&partnerID=40&md5=2b6c42ae87ab7aafdbcd93bad4f03804 |
en |
| dc.subject.other |
1,2 hexadecanediamine |
en |
| dc.subject.other |
1,3 heptadecanediamine |
en |
| dc.subject.other |
2 aminohexadecanol |
en |
| dc.subject.other |
diamine |
en |
| dc.subject.other |
unclassified drug |
en |
| dc.subject.other |
antiinflammatory activity |
en |
| dc.subject.other |
article |
en |
| dc.subject.other |
drug synthesis |
en |
| dc.subject.other |
nonhuman |
en |
| dc.subject.other |
nuclear magnetic resonance spectroscopy |
en |
| dc.subject.other |
paw edema |
en |
| dc.subject.other |
rat |
en |
| dc.subject.other |
Alkanes |
en |
| dc.subject.other |
Amines |
en |
| dc.subject.other |
Amino Alcohols |
en |
| dc.subject.other |
Animals |
en |
| dc.subject.other |
Anti-Inflammatory Agents |
en |
| dc.subject.other |
Diamines |
en |
| dc.subject.other |
Edema |
en |
| dc.subject.other |
Lipids |
en |
| dc.subject.other |
Magnetic Resonance Spectroscopy |
en |
| dc.subject.other |
Molecular Mimicry |
en |
| dc.subject.other |
Rats |
en |
| dc.title |
Synthetic routes to lipidic diamines and amino alcohols: A class of potential antiinflammatory agents |
en |
| heal.type |
journalArticle |
en |
| heal.publicationDate |
1999 |
en |
| heal.abstract |
Simple and efficient methods for the synthesis of lipidic amino alcohols and diamines are described in this paper. Lipidic 2-amino alcohols and 1,3- diamines can be synthesized starting from synthetic lipidic α-amino acids. Alternatively, commercially available lipidic 1,2-diols may be used as starting material for the synthesis of 2-amino alcohols. Initial experiments on the in vivo antiinflammatory activity of the compounds synthesized gave promising results. |
en |
| heal.journalName |
Lipids |
en |
| dc.identifier.issue |
3 |
en |
| dc.identifier.volume |
34 |
en |
| dc.identifier.spage |
307 |
en |
| dc.identifier.epage |
311 |
en |