| dc.contributor.author |
Couladouros, EA |
en |
| dc.contributor.author |
Li, T |
en |
| dc.contributor.author |
Moutsos, VI |
en |
| dc.contributor.author |
Pitsinos, EN |
en |
| dc.contributor.author |
Soufli, IC |
en |
| dc.date.accessioned |
2014-06-06T06:43:59Z |
|
| dc.date.available |
2014-06-06T06:43:59Z |
|
| dc.date.issued |
1999 |
en |
| dc.identifier.issn |
0960894X |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1016/S0960-894X(99)00503-X |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/1603 |
|
| dc.subject.other |
combretastatin |
en |
| dc.subject.other |
combretastatin d derivative |
en |
| dc.subject.other |
tubulin |
en |
| dc.subject.other |
unclassified drug |
en |
| dc.subject.other |
article |
en |
| dc.subject.other |
cell line |
en |
| dc.subject.other |
microtubule |
en |
| dc.subject.other |
molecular interaction |
en |
| dc.subject.other |
polymerization |
en |
| dc.subject.other |
structure activity relation |
en |
| dc.subject.other |
Bibenzyls |
en |
| dc.subject.other |
Microtubules |
en |
| dc.subject.other |
Molecular Structure |
en |
| dc.subject.other |
Stilbenes |
en |
| dc.title |
Stabilization of microtubules by Combretastatin D derivatives |
en |
| heal.type |
journalArticle |
en |
| heal.identifier.primary |
10.1016/S0960-894X(99)00503-X |
en |
| heal.publicationDate |
1999 |
en |
| heal.abstract |
The effect of five derivatives of Combretastatin D on tubulin polymerization was investigated. All of them were found to stabilize microtubules to various degrees. The derivatives bearing polar substituents were found to be the most active. |
en |
| heal.journalName |
Bioorganic and Medicinal Chemistry Letters |
en |
| dc.identifier.issue |
20 |
en |
| dc.identifier.volume |
9 |
en |
| dc.identifier.doi |
10.1016/S0960-894X(99)00503-X |
en |
| dc.identifier.spage |
2927 |
en |
| dc.identifier.epage |
2928 |
en |