Prediction of lipid accumulation-degradation in oleaginous micro-organisms growing on vegetable oils

dc.contributor.author	Aggelis, G	en
dc.contributor.author	Sourdis, J	en
dc.date.accessioned	2014-06-06T06:43:25Z
dc.date.available	2014-06-06T06:43:25Z
dc.date.issued	1997	en
dc.identifier.issn	00036072	en
dc.identifier.uri	http://dx.doi.org/10.1023/A:1000364402110	en
dc.identifier.uri	http://62.217.125.90/xmlui/handle/123456789/1254
dc.subject	Accumulation-degradation	en
dc.subject	Modelling	en
dc.subject	Oleaginous micro-organisms	en
dc.subject	Vegetable oil	en
dc.subject.other	carbon	en
dc.subject.other	vegetable oil	en
dc.subject.other	article	en
dc.subject.other	biomass	en
dc.subject.other	cell growth	en
dc.subject.other	growth rate	en
dc.subject.other	lipid metabolism	en
dc.subject.other	lipid storage	en
dc.subject.other	mathematical model	en
dc.subject.other	mould	en
dc.subject.other	nonhuman	en
dc.subject.other	priority journal	en
dc.subject.other	yeast	en
dc.subject.other	Biomass	en
dc.subject.other	Lipid Metabolism	en
dc.subject.other	Models, Biological	en
dc.subject.other	Plant Oils	en
dc.subject.other	Yeasts	en
dc.title	Prediction of lipid accumulation-degradation in oleaginous micro-organisms growing on vegetable oils	en
heal.type	journalArticle	en
heal.identifier.primary	10.1023/A:1000364402110	en
heal.publicationDate	1997	en
heal.abstract	Oleaginous micro-organisms (yeasts, moulds), in culture media having the carbon source as limited factor, degrade reserve lipids and produce new biomass, after the onset of carbon exhaustion from the medium. In this paper the process of lipid accumulation-degradation in oleaginous micro-organisms, growing on a vegetable oil was simulated. The model was integrated with 4 different methods and the parameters were optimised with the least squares method. It was found that the degradation of endocellular carbon pool is a very slow process characterised, however, by a good yield in fat-free biomass. Low values of the specific growth rates of the fat-free microbial mass, both from consumption of extracellular and endocellular carbon pools, favourite the production of microbial lipid. The maximum of the specific rate of lipid accumulation is positively affected by the low values of the specific growth rate of the fat-free microbial mass from consumption of extracellular carbon pool, but remained unaffected by the specific growth rate of the fat-free microbial mass from consumption of endocellular carbon pool. On the other hand, lipid production and specific rate of lipid accumulation are positively influenced by the high values of the specific rate of storage lipid formation. In conclusion, this numerical model can be used in the laboratory as pilot for planing further experimental work.	en
heal.journalName	Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology	en
dc.identifier.issue	2	en
dc.identifier.volume	72	en
dc.identifier.doi	10.1023/A:1000364402110	en
dc.identifier.spage	159	en
dc.identifier.epage	165	en