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Pituitary responsiveness to GnRH in lambs undernourished during fetal life

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dc.contributor.author Deligeorgis, SG en
dc.contributor.author Chadio, S en
dc.contributor.author Menegatos, J en
dc.date.accessioned 2014-06-06T06:43:12Z
dc.date.available 2014-06-06T06:43:12Z
dc.date.issued 1996 en
dc.identifier.issn 03784320 en
dc.identifier.uri http://62.217.125.90/xmlui/handle/123456789/1083
dc.relation.uri http://www.scopus.com/inward/record.url?eid=2-s2.0-0001079961&partnerID=40&md5=146b3d54934029d40e861f6f22cbea41 en
dc.subject Lamb en
dc.subject LH en
dc.subject Pituitary activity en
dc.subject Undernourishment en
dc.title Pituitary responsiveness to GnRH in lambs undernourished during fetal life en
heal.type journalArticle en
heal.publicationDate 1996 en
heal.abstract A study was conducted to investigate the effect of undernutrition in utero on pituitary responsiveness to GnRH stimulation in lambs after birth. Thirty-four lambs were used which were born to ewes fed 110% of the energy maintenance plus two embryos requirements during pregnancy (control, C) or 90% of the maintenance with no additional allowances for embryo growth (restricted, R) from 30 day of pregnancy to lambing. A GnRH stimulation test was performed on all lambs at 55 days of age. The average energy consumed daily by each ewe in the R group was only the 60% of that consumed by the ewes in the C group. Following injection of GnRH, peak LH values were observed within 15 min in both groups. Animals in Group C (n = 19) showed a significantly greater LH response than animals in Group R (n = 15) at 15 min and at 30 min post-injection (43.3 vs. 33.9 and 39.0 vs. 32.2 ng m1-1, respectively). The significant treatment X time interaction found revealed that the rate of increase of LH concentration above the basal value within the first 15 min after GnRH administration was higher in C than in R lambs, while the rate of decrease from 30 to 120 min was lower in R than in C lambs. It was concluded that the timing as well as the magnitude of maternal undernutrition may be significant factors affecting the subsequent reproductive potential of the progeny in sheep by reducing pituitary activity. en
heal.journalName Animal Reproduction Science en
dc.identifier.issue 2-3 en
dc.identifier.volume 43 en
dc.identifier.spage 113 en
dc.identifier.epage 121 en


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