| dc.contributor.author |
Korakas, D |
en |
| dc.contributor.author |
Kimbaris, A |
en |
| dc.contributor.author |
Varvounis, G |
en |
| dc.date.accessioned |
2014-06-06T06:43:08Z |
|
| dc.date.available |
2014-06-06T06:43:08Z |
|
| dc.date.issued |
1996 |
en |
| dc.identifier.uri |
http://dx.doi.org/10.1016/0040-4020(96)00597-2 |
en |
| dc.identifier.uri |
http://62.217.125.90/xmlui/handle/123456789/1034 |
|
| dc.title |
Synthesis of the novel pyrrolo[2,1-d][1,2,5]benzotriazepine, pyrrolo[2,1-e][1,3,6]benzotriazocine and pyrrolo[1,2-a]tetrazolo[1,5-d][1,4]benzodiazepine ring systems. A new route to pyrrolo[1,2-a]quinoxaline via transamination of in situ generated 1-(2-aminophenyl)-2-iminomethylpyrroles |
en |
| heal.type |
journalArticle |
en |
| heal.identifier.primary |
10.1016/0040-4020(96)00597-2 |
en |
| heal.publicationDate |
1996 |
en |
| heal.abstract |
Selective reduction of 2-azidomethyl-1-(2-nitrophenyl)pyrrole 5 afforded 2-aminomethyl-1-(2-nitrophenyl)pyrrole 10. Pyrrolo[1,2-a]quinoxaline 15 is obtained by treating aminoester 12 with formaldehyde. Diamine 8 reacts with either formaldehyde or benzaldehyde to give pyrrolo[1,2-a]quinoxaline 19. Compound 10 was reductively cyclised to pyrrolo[2,1-d][1,2,5]-benzotriazepine 22. Intramolecular coupling of diamine 8 with triphosgene or carbon disulfide yields pyrrolo[2,1-e][1,3,6]benzotriazocine 23 and 24, respectively. Intramolecular 1,3-dipolar cycloaddition of cyanoazide 6 |
en |
| heal.journalName |
Tetrahedron |
en |
| dc.identifier.doi |
10.1016/0040-4020(96)00597-2 |
en |